Musculoskeletal pain:
Indications for Chlorzoxazone:
As adjunct to rest, physical therapy, and other measures in acute, painful musculoskeletal conditions.
Adult:
375mg: 1 tab 3–4 times daily; may increase to 2 tabs (750mg) 3–4 times daily if inadequate response. 750mg: ⅓ tab (250mg) 3–4 times daily. Painful musculoskeletal conditions: initially ⅔ tab (500mg) 3–4 times daily; may increase to 1 tab (750mg) 3–4 times daily if inadequate response. May reduce dose based on improvement.
Children:
Not recommended.
Contraindications:
Known drug intolerance.
Warnings/Precautions:
Monitor for hepatotoxicity; discontinue if hepatic dysfunction or abnormal liver enzymes develop. Known allergies or history of. Discontinue if sensitivity reaction occurs. Pregnancy.
Pharmacologic Class:
Muscle relaxant (central).
Interactions:
Additive effects with concomitant alcohol, other CNS depressants.
Adverse Reactions:
Drowsiness, dizziness, lightheadedness, malaise, overstimulation; rare: skin rash, petechiae, ecchymosis, fatal hepatocellular toxicity.
Note:
Formerly known under the brand name Lorzone, Paraflex.
How Supplied:
Contact supplier
