Select therapeutic use:

Nausea:

Indications for Chlorpromazine injection:

Nausea and vomiting.

Adult Dosage:

25–50mg IM every 3–4hrs if needed.

Children Dosage:

<6months: not recommended. ≥6months: 0.25mg/lb IM every 6–8hrs if needed. <5yrs or <50lbs: max 40mg/day; ≥5yrs or 50–100lbs: usual max 75mg/day.

Chlorpromazine injection Contraindications:

Coma. CNS or bone marrow depression. Reye's syndrome.

Chlorpromazine injection Warnings/Precautions:

Discontinue 48 hrs before to 24 hrs after myelography. Cardiovascular, respiratory, renal, or liver disease. Epilepsy. Glaucoma. History of breast cancer. Exposure to extreme heat or organophosphates. Asthma (inj). Monitor blood, liver, and ocular function. Elderly. Pregnancy, nursing mothers: not recommended.

See Also:

Chlorpromazine injection Classification:

Phenothiazine.

Chlorpromazine injection Interactions:

Potentiates phenytoin, alcohol, other CNS depressants, propranolol. Potentiated by propranolol. Antagonized by anticholinergics. Atropine. Decreased guanethidine, anticoagulant effects.

Adverse Reactions:

Tardive dyskinesia, drowsiness, jaundice, blood dyscrasias, hypotension, retinopathy, may mask emetic signs of disease, lowered seizure threshold, rash, skin pigmentation, anticholinergic effects, insomnia, extrapyramidal reactions, neuroleptic malignant syndrome.

Note:

Formerly known under the brand name Thorazine.

How Supplied:

Contact supplier.

Psychosis:

Indications for Chlorpromazine injection:

Rapid control of severe psychotic symptoms. Severe childhood behavior disorders. Adjunct in tetanus.

Adult Dosage:

Psychosis: 25mg IM; may repeat in 1 hour, then switch to oral forms. Tetanus: 25–50mg IM 3–4 times daily or 25–50mg IV (see literature).

Children Dosage:

<6months: not recommended. ≥6months: Severe behavior disorders: 0.25mg/lb IM every 6–8 hrs if needed. Tetanus: 0.25mg/lb IM or IV (see literature) every 6–8 hrs. Both: <5yrs or <50lbs: max 40mg/day; ≥5yrs or 50–100lbs: usual max 75mg/day.

Chlorpromazine injection Contraindications:

Coma. CNS or bone marrow depression. Reye's syndrome.

Chlorpromazine injection Warnings/Precautions:

Discontinue 48 hrs before to 24 hrs after myelography. Cardiovascular, respiratory, renal, or liver disease. Epilepsy. Glaucoma. History of breast cancer. Exposure to extreme heat or organophosphates. Asthma (inj). Monitor blood, liver, and ocular function. Elderly. Pregnancy, nursing mothers: not recommended.

See Also:

Chlorpromazine injection Classification:

Aliphatic phenothiazine.

Chlorpromazine injection Interactions:

Potentiates phenytoin, alcohol, other CNS depressants, propranolol. Potentiated by propranolol. Antagonized by anticholinergics. Atropine. Decreased guanethidine, anticoagulant effects.

Adverse Reactions:

Tardive dyskinesia, drowsiness, jaundice, blood dyscrasias, hypotension, retinopathy, may mask emetic signs of disease, lowered seizure threshold, rash, skin pigmentation, anticholinergic effects, insomnia, extrapyramidal reactions, neuroleptic malignant syndrome.

Note:

Formerly known under the brand name Thorazine.

How Supplied:

Contact supplier.