• Nausea

Cesamet Generic Name & Formulations

General Description

Nabilone 1mg; caps.

Pharmacological Class


How Supplied


Cesamet Indications


Treatment of nausea and vomiting associated with cancer chemotherapy in patients who have not responded adequately to other antiemetics.

Cesamet Dosage and Administration


1–2mg twice daily; max 6mg/day in 3 divided doses. Give 1st dose 1–3 hours before chemotherapy is administered; use lower starting dose and increase if necessary. May give 1–2mg the night before chemo. Continue 2–3 doses/day during chemotherapy course, if needed, may continue 48 hours after each chemo cycle.


<18yrs: not recommended.

Cesamet Contraindications

Not Applicable

Cesamet Boxed Warnings

Not Applicable

Cesamet Warnings/Precautions


Hypertension. Heart disease. History of psychiatric disorders (eg, bipolar disorder, depression, schizophrenia) or substance abuse. Write ℞ for limited quantity (ie, enough for one chemotherapy course). Keep patient under responsible adult supervision (esp. when dose is adjusted). Renal or hepatic impairment. Elderly. Pregnancy (Cat.C). Nursing mothers: not recommended.

Cesamet Pharmacokinetics

See Literature

Cesamet Interactions


Potentiates CNS depression with benzodiazepines, barbiturates, alcohol, other CNS depressants and other psychoactive substances (avoid). May affect, or be affected by, other drugs that undergo first-pass hepatic metabolism or that are highly protein bound (eg, sympathomimetics, anticholinergics, tricyclic antidepressants). Cross-tolerance and mutual potentiation with opioids. Naltrexone: see literature.

Cesamet Adverse Reactions

Adverse Reactions

Drowsiness, vertigo, dry mouth, euphoria/dysphoria, ataxia, headache, tachycardia, hypotension, concentration difficulties, sleep disturbance, other psychiatric reactions (may persist for several days after dosing), changes in appetite.

Cesamet Clinical Trials

See Literature

Cesamet Note

Not Applicable

Cesamet Patient Counseling

See Literature