• Labor and delivery

Cervidil Generic Name & Formulations

General Description

Dinoprostone 10mg; controlled-release vaginal insert w. retrieval system.

How Supplied


Cervidil Indications


Cervical ripening in patients at or near term when there is an indication for labor induction.

Cervidil Dosage and Administration


See full labeling.


Not established.

Cervidil Contraindications


Evidence or suspicion of fetal distress where delivery is not imminent. Unexplained vaginal bleeding. Evidence or suspicion of marked cephalopelvic disproportion. Conditions for which labor induction, oxytocics are inappropriate or prolonged uterine contractions may be detrimental to fetal safety. Previous cesarean section or other uterine surgery expected to affect uterine integrity (eg, myomectomy). Six or more previous term pregnancies. Concomitant IV oxytocics.

Cervidil Boxed Warnings

Not Applicable

Cervidil Warnings/Precautions


For hospital use when appropriate obstetric care is present. Increased risk of postpartum disseminated intravascular coagulation (eg, ≥30yrs of age, complications during pregnancy, gestational age >40weeks); assess for evolving fibrinolysis in the immediate postpartum period. Monitor for amniotic fluid embolism syndrome. Glaucoma. Monitor uterine activity, fetal status, cervical dilatation/effacement. Remove insert if uterine tachysystole, uterine hypersystole/hypertonicity, fetal distress, or if labor commences, and prior to amniotomy or following rupture of membranes. Pregnancy.

Cervidil Pharmacokinetics

See Literature

Cervidil Interactions


Potentiates oxytocics; delay administration of oxytocics at least 30mins after removal of insert.

Cervidil Adverse Reactions

Adverse Reactions

Uterine tachysystole with/without fetal distress, fetal distress without uterine tachysystole.

Cervidil Clinical Trials

See Literature

Cervidil Note

Not Applicable

Cervidil Patient Counseling

See Literature