Cefpodoxime Proxetil

  • Bacterial infections

Cefpodoxime Proxetil Generic Name & Formulations

General Description

Cefpodoxime proxetil 100mg, 200mg; tabs.

Pharmacological Class


How Supplied

Contact supplier.

Cefpodoxime Proxetil Indications


Susceptible mild to moderate infections including acute otitis media, acute bacterial exacerbations of chronic bronchitis, acute maxillary sinusitis, pharyngitis/tonsillitis, acute community-acquired pneumonia, urinary tract, skin and skin structures; cervical, anorectal (females only) and urethral gonorrhea.

Cefpodoxime Proxetil Dosage and Administration


Take tabs with food. ≥13yrs: Pneumonia: 200mg every 12hrs for 14 days. Bronchitis, sinusitis: 200mg every 12hrs for 10 days. Pharyngitis/tonsillitis: 100mg every 12hrs for 5–10 days. Skin and skin structures: 400mg every 12hrs for 7–14 days. UTI: 100mg every 12hrs for 7 days. Uncomplicated gonorrhea: 200mg once as a single dose. Renal failure or hemodialysis: see full labeling.


Use susp. <2 months: not recommended. 2 months–12yrs: Acute otitis media: 5mg/kg (max 200mg) every 12hrs for 5 days. Pharyngitis/tonsillitis: 5mg/kg (max 100mg) every 12hrs for 5–10 days. Sinusitis: 5mg/kg (max 200mg) every 12hrs for 10 days.

Cefpodoxime Proxetil Contraindications

Not Applicable

Cefpodoxime Proxetil Boxed Warnings

Not Applicable

Cefpodoxime Proxetil Warnings/Precautions


Penicillin or other allergy. Labor & delivery. Pregnancy (Cat.B). Nursing mothers: not recommended.

Cefpodoxime Proxetil Pharmacokinetics

See Literature

Cefpodoxime Proxetil Interactions


Antacids, H2 antagonists, oral anticholinergics may decrease efficacy. Potentiated by probenecid. Avoid concomitant diuretics, other nephrotoxic drugs. May cause false (+) direct Coomb's test.

Cefpodoxime Proxetil Adverse Reactions

Adverse Reactions

GI upset, abdominal pain, headache, rash, anaphylaxis.

Cefpodoxime Proxetil Clinical Trials

See Literature

Cefpodoxime Proxetil Note


Formerly known under the brand name Vantin.

Cefpodoxime Proxetil Patient Counseling

See Literature