Cefoxitin Injection

  • Bacterial infections

Cefoxitin Injection Generic Name & Formulations

General Description

Cefoxitin sodium 1g, 2g; for IV inj; sodium content 2.3mEq/g.

Pharmacological Class


How Supplied

Contact supplier.

Cefoxitin Injection Indications


Susceptible bacterial septicemia, lower respiratory or urinary tract, skin and skin structure, bone and joint, gynecologic, intraabdominal infections. Surgical prophylaxis.

Cefoxitin Injection Dosage and Administration


Usually 1–2g every 6–8hrs. Uncomplicated: 1g every 6–8hrs. Moderately severe to severe: 1g every 4hrs or 2g every 6–8hrs. Max 2g every 4hrs or 3g every 6hrs. Prophylaxis: see literature.


<3months: not recommended. ≥3months: 80–160mg/kg per day in 4–6 equal divided doses; max 12g/day. Prophylaxis: see literature.

Cefoxitin Injection Contraindications

Not Applicable

Cefoxitin Injection Boxed Warnings

Not Applicable

Cefoxitin Injection Warnings/Precautions


Penicillin or other allergy. Renal impairment (CrCl <50mL/min), reduce dose: see literature. GI disease (esp. colitis). Pregnancy (Cat.B). Nursing mothers.

Cefoxitin Injection Pharmacokinetics

See Literature

Cefoxitin Injection Interactions


Aminoglycosides may potentiate nephrotoxicity. Potentiated by probenecid. May cause false (+) Clinitest. May interfere with creatinine tests.

Cefoxitin Injection Adverse Reactions

Adverse Reactions

Local reactions, rash, pruritus, drug fever, GI upset, anaphylaxis, blood dyscrasias, elevated liver enzymes.

Cefoxitin Injection Clinical Trials

See Literature

Cefoxitin Injection Note


Formerly known under the brand name Mefoxin.

Cefoxitin Injection Patient Counseling

See Literature