Cefotan

IV: inject over 3–5mins. UTI: 500mg IV or IM every 12hrs or 1–2g IV or IM every 12–24hrs. Mild to moderate skin and skin structures: 2g IV every 24hrs or 1g IV or IM every 12hrs. Severe skin and skin structure: 2g IV every 12hrs. Other sites: 1–2g IV or IM every 12hrs. Severe: 2g IV every 12hrs. Life threatening: 3g IV every 12hrs; max 6g/day. Prophylaxis: 1–2g IV once 30–60 mins before surgery. CrCl <30mL/min: reduce dose or frequency, see full labeling. Hemodialysis: give ¼ of the usual dose every 24hrs on days between dialysis and ½ the usual dose on dialysis days.