Cefaclor Extended-release Generic Name & Formulations
Cefaclor 375mg, 500mg; ext-rel tabs.
Cefaclor Extended-release Indications
Susceptible mild to moderate infections including acute exacerbations of chronic bronchitis, secondary infections of acute bronchitis, pharyngitis/tonsillitis, uncomplicated skin and skin structures.
Cefaclor Extended-release Dosage and Administration
Take with meals. Swallow whole. Cefaclor ext-rel tab 500mg twice daily clinically equivalent to caps 250mg three times daily. ≥16yrs: Bronchitis: 500mg every 12 hrs for 7 days. Pharyngitis/tonsillitis: 375mg every 12 hrs for 10 days. Skin and skin structures: 375mg every 12 hrs for 7–10 days.
<16yrs: not recommended.
Cefaclor Extended-release Contraindications
Cefaclor Extended-release Boxed Warnings
Cefaclor Extended-release Warnings/Precautions
Penicillin or other allergy. Discontinue if colitis occurs and treat. Severe renal dysfunction. GI disease (esp. colitis). Pregnancy (Cat.B). Nursing mothers.
Cefaclor Extended-release Pharmacokinetics
Cefaclor Extended-release Interactions
May cause false (+) Coomb's test or glucose test with Clinitest or Benedict's or Fehling's soln. Potentiated by probenecid. Monitor warfarin. ER: antagonized by concomitant (within 1 hr) aluminum or magnesium-containing antacids.
Cefaclor Extended-release Adverse Reactions
Headache, GI upset, rash, blood dyscrasias, hepatic dysfunction, cough, CNS stimulation, serum-sickness-like reactions.
Cefaclor Extended-release Clinical Trials
Cefaclor Extended-release Note
Formerly known under the brand names Ceclor CD (ext-rel tabs); Ceclor (caps, susp); Raniclor (caps).
Cefaclor Extended-release Patient Counseling