Cayston Generic Name & Formulations
Aztreonam 75mg/vial; pwd for inhalation via nebulization after reconstitution; preservative-free.
Vials—84 (w. diluent)
To improve respiratory symptoms in cystic fibrosis patients with Pseudomonas aeruginosa.
Cayston Dosage and Administration
Adults and Children
<7yrs: not established. Use a short-acting bronchodilator 15 minutes to 4 hours before each dose; or a long-acting bronchodilator 30 minutes to 12 hours before starting therapy. >7yrs: 75mg (1 vial) by nebulization three times daily (at least 4 hours apart) for 28 days. Use Altera Nebulizer only.
Cayston Boxed Warnings
Monobactam or beta-lactam allergy. FEV<25% or >75% predicted, patients colonized with Burkholderia cepacia: safety/effectiveness not established. Pregnancy. Nursing mothers.
Do not mix with other drugs in nebulizer.
Cayston Adverse Reactions
Cough, nasal congestion, wheezing, pharyngolaryngeal pain, pyrexia, chest discomfort, abdominal pain, vomiting, rash; chest tightness, bronchospasm, allergic reactions (discontinue if occurs).
Cayston Clinical Trials
To support and assist patients with cystic fibrosis contact the Cayston Access Program at (877) 7CAYSTON. Should be administered immediately after reconstitution. Do not reconstitute until ready to administer a dose.
Cayston Patient Counseling