• Hypertension

Catapres-tts Generic Name & Formulations

General Description

Clonidine 0.1mg/day, 0.2mg/day, 0.3mg/day; each transdermal patch delivers dose for 1 week.

Pharmacological Class

Central alpha agonist.

See Also

How Supplied

Tabs—100; Patch—4

Catapres-tts Indications



Catapres-tts Dosage and Administration


Apply to intact, hairless area of upper arm or anterior torso; rotate application sites. Taper withdrawal of other antihypertensives. Initially one 0.1mg/day patch weekly; may increase after 1–2 weeks; max 0.6mg/day.


Not established.

Catapres-tts Contraindications

Not Applicable

Catapres-tts Boxed Warnings

Not Applicable

Catapres-tts Warnings/Precautions


Sinus node dysfunction. AV block. Pheochromocytoma: not effective. Conduction disturbances. Renal dysfunction. Avoid abrupt cessation. If local reaction occurs from patch, using tabs may cause generalized rash. Discontinue 4hrs before surgery; resume as soon as possible after surgery. Patch: remove before defibrillation, cardioversion, or MRI. Pregnancy (Cat.C). Nursing mothers.

Catapres-tts Pharmacokinetics

See Literature

Catapres-tts Interactions


Antagonized by tricyclic antidepressants. Potentiates CNS depressants. Orthostatic regulation disturbances (eg, orthostatic hypotension, dizziness, fatigue) possible with neuroleptics. Monitor heart rate in patients receiving agents known to affect sinus node function or AV nodal conduction (eg, digitalis, calcium channel blockers, β-blockers).

Catapres-tts Adverse Reactions

Adverse Reactions

Dry mouth, dry eye, drowsiness, dizziness, weakness, constipation, sedation, rash, myalgia, urticaria, nausea, insomnia, agitation, orthostatic hypotension, impotence, arrhythmias.

Catapres-tts Clinical Trials

See Literature

Catapres-tts Note

Not Applicable

Catapres-tts Patient Counseling

See Literature