Cardene Iv

  • Hypertension

Cardene Iv Generic Name & Formulations

General Description

Nicardipine HCl 2.5mg/mL; soln for slow IV infusion (after dilution to 0.1mg/mL).

Pharmacological Class

Calcium channel blocker (CCB) (dihydropyridine).

How Supplied

Caps 20mg, 30mg—contact supplier; IV (10mL amps)—10; Premixed—200mL


Cardene Iv Indications


Short-term treatment of hypertension when oral therapy is not feasible or desirable.

Cardene Iv Dosage and Administration


Individualize; see full labeling.


<18yrs: not established.

Cardene Iv Contraindications


Advanced aortic stenosis.

Cardene Iv Boxed Warnings

Not Applicable

Cardene Iv Warnings/Precautions


Angina. Heart failure. Acute cerebral infarction or hemorrhage. Hepatic or renal impairment. Pheochromocytoma. For caps: measure blood pressure (BP) 1–2 hrs and 8 hrs after dosing. For IV: monitor BP before and during infusion; avoid rapid or excessive reductions, intra-arterial administration or extravasation; switch to oral form when possible. Pregnancy (Cat.C). Nursing mothers: not recommended.

Cardene Iv Pharmacokinetics

See Literature

Cardene Iv Interactions


Potentiated by cimetidine. Increases serum levels of cyclosporine, tacrolimus; monitor and adjust its dose. Possibly potentiates digoxin; monitor.

Cardene Iv Adverse Reactions

Adverse Reactions

Increased angina, flushing (caps), headache, pedal edema, asthenia, dizziness, somnolence (caps), tachycardia, GI upset, sweating; ECG abnormalities, orthostatic hypotension, ventricular extrasystoles, local reactions (inj).

Cardene Iv Clinical Trials

See Literature

Cardene Iv Note

Not Applicable

Cardene Iv Patient Counseling

See Literature