Butorphanol Nasal Spray Generic Name & Formulations
Butorphanol tartrate 1mg/spray; nasal spray.
Nasal Spray 2.5mL (8–15 sprays)—Contact supplier.
Butorphanol Nasal Spray Indications
Pain management when opioid analgesia is appropriate.
Butorphanol Nasal Spray Dosage and Administration
≥18 years: initially 1 spray in 1 nostril, repeat after 60–90 minutes if needed (Elderly: 90–120 minutes); may repeat in 3–4 hours. Or, may give 1 spray in each nostril, may repeat after 3–4 hours.
<18 years: not recommended.
Butorphanol Nasal Spray Contraindications
Butorphanol Nasal Spray Boxed Warnings
Butorphanol Nasal Spray Warnings/Precautions
Head injury. Increased intracranial pressure. Biliary tract surgery. Respiratory, cardiac, renal, or hepatic dysfunction. MI. Ventricular dysfunction. Coronary insufficiency. Hypertension. May precipitate withdrawal in narcotic addicts. Elderly. Labor & delivery. Pregnancy (Cat.C). Nursing mothers.
Butorphanol Nasal Spray Pharmacokinetics
Butorphanol Nasal Spray Interactions
Potentiates CNS depression with alcohol, other CNS depressants. Nasal vasoconstrictors delay onset. May be antagonized by concomitant (within 30 minutes) sumatriptan nasal spray.
Butorphanol Nasal Spray Adverse Reactions
Sedation, dizziness, nasal congestion, insomnia, GI upset, respiratory depression, sweating, hypo- or hypertension, rash, vasodilation, palpitation, tinnitus, respiratory and CNS effects.
Butorphanol Nasal Spray Clinical Trials
Butorphanol Nasal Spray Note
Formerly known under the brand name Stadol NS.
Butorphanol Nasal Spray Patient Counseling