Edema:

Indications for Bumetanide Tablets:

Edema.

Adult:

0.5mg–2mg daily; max 10mg daily. Intermittent dosing optimal.

Children:

<18yrs: not recommended.

Contraindications:

Anuria. Hepatic coma. Severe electrolyte depletion.

Warnings/Precautions:

Hepatic cirrhosis. Ascites. Sulfonamide allergy. Progressive renal disease. Gout. Diabetes. Postsympathectomy. Monitor electrolytes, blood, liver function. Potassium supplementation may be needed. Potassium-losing nephropathy. Aldosterone excess. Discontinue if renal dysfunction progresses. Ventricular arrhythmias. Elderly. Pregnancy (Cat.C). Nursing mothers: not recommended.

Pharmacologic Class:

Diuretic (loop).

Interactions:

May increase digitalis, lithium toxicity. Hypokalemia with digitalis, diuretics in CHF. Alcohol, CNS depressants may increase orthostatic hypotension. Avoid probenecid, indomethacin. Ototoxicity may be potentiated with aminoglycosides.

Adverse Reactions:

Muscle cramps, dizziness, hypotension, headache, nausea, encephalopathy, ototoxicity, rash, fluid or electrolyte imbalance, hyperglycemia, hyperuricemia, blood dyscrasias.

Note:

Formerly known under the brand name Bumex.

How Supplied:

Contact supplier.