Indications for: Bumetanide Injection


Adult Dosage:

Initially 0.5–1mg IM or IV. May give 1–2 more doses at 2–3 hour intervals; max 10mg/day.

Children Dosage:

<18yrs: not established.

Bumetanide Injection Contraindications:

Anuria. Infants. Hepatic coma. Severe electrolyte depletion.

Bumetanide Injection Warnings/Precautions:

Hepatic cirrhosis. Ascites. Progressive renal disease. Gout. Diabetes. Postsympathectomy. Monitor electrolytes, blood, liver function. May need K+ supplementation. K+ losing nephropathy. Discontinue if renal dysfunction progresses. Aldosterone excess. Ventricular arrhythmias. Elderly. Pregnancy (Cat.C). Nursing mothers: not recommended.

Bumetanide Injection Classification:

Diuretic (loop).

Bumetanide Injection Interactions:

May increase digitalis, lithium toxicity. Hypokalemia with digitalis, diuretics in CHF. Alcohol, CNS depressants increase orthostatic hypotension. Avoid probenecid, indomethacin. Ototoxicity may be potentiated with aminoglycosides.

Adverse Reactions:

Muscle cramps, dizziness, hypotension, headache, nausea, encephalopathy, ototoxicity, rash, fluid or electrolyte imbalance, hyperglycemia, hyperuricemia, blood dyscrasias.


Formerly known under the brand name Bumex.

How Supplied:

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