Indications for: BROVANA

Long-term maintenance treatment of bronchoconstriction in COPD, including chronic bronchitis and emphysema.

Limitations of Use:

Not indicated to treat acute deteriorations of COPD or for treatment of asthma.

Adult Dosage:

By nebulizer: 15mcg by inhalation twice daily (AM & PM); max 30mcg/day. Use standard jet (eg, PARI LC Plus) nebulizer with air compressor (eg, PARI DURA-NEB 3000). Reevaluate periodically.

Children Dosage:

Not established.

BROVANA Contraindications:

Use of LABA without inhaled corticosteroid (ICS) in asthma.

BROVANA Warnings/Precautions:

LABA as monotherapy (without ICS) for asthma can increase risk of asthma-related events. Do not initiate in acute deteriorating COPD. Not for relief of acute symptoms. Prescribe a short-acting β2-agonist for acute symptoms; monitor for increased need. Do not exceed recommended dose. Discontinue if paradoxical bronchospasm or cardiovascular effects occur. Cardiovascular disease (esp. coronary insufficiency, arrhythmias, hypertension). Convulsive disorders. Thyrotoxicosis. Hyperresponsiveness to sympathomimetics. Diabetes. Ketoacidosis. Hypokalemia. Monitor potassium and blood glucose levels. Hepatic impairment. Pregnancy. Labor & delivery. Nursing mothers.

BROVANA Classification:

Long-acting beta-2 agonist (LABA).

BROVANA Interactions:

See Contraindications. Avoid other sympathomimetics (except short-acting bronchodilators). Caution with MAOIs, tricyclics, or drugs known to prolong the QTc interval; may increase risk of arrhythmias. Antagonized by β-blockers. K+-depleting diuretics, theophylline, aminophylline, steroids may potentiate hypokalemia.

Adverse Reactions:

Pain, chest pain, back pain, diarrhea, sinusitis, leg cramps, dyspnea, rash, flu syndrome, peripheral edema, lung disorder; cardiovascular effects (eg, increased pulse rate or BP, ECG changes); rarely: paradoxical bronchospasm, hypersensitivity reactions.

Generic Drug Availability:


How Supplied:

Vials (2mL)—30, 60

Pricing for BROVANA

2ml of 15mcg/2ml vial (Qty: 60)
Appx. price $120