Brevibloc Double Strength

Supraventricular tachycardia: Initial loading dose: 0.5mg/kg infused over 1 minute followed by maintenance infusion of 0.05mg/kg/min for the next 4 minutes. After the 4 minutes of initial maintenance infusion, depending upon desired ventricular response, may continue maintenance infusion at 0.05mg/kg/min or increase step-wise (eg, 0.1mg/kg/min, 0.15mg/kg/min, to max 0.2mg/kg/min) with each step being maintained for 4 or more minutes. If more rapid slowing of ventricular response is imperative, the 0.5mg/kg loading dose infused over a 1 minute period may be repeated, followed by a maintenance infusion of 0.1mg/kg/min for 4 minutes. Then, depending upon ventricular rate, another (and final) loading dose of 0.5mg/kg/min infused over a 1 minute period may be given followed by a maintenance infusion of 0.15mg/kg/min. If needed, after 4 minutes of the 0.15mg/kg/min maintenance infusion, the maintenance infusion may be increased to a maximum of 0.2mg/kg/min. See literature for transitioning to alternative antiarrhythmic agent. Intraoperative and postoperative tachycardia and/or hypertension: Immediate control: 80mg bolus dose over 30 seconds followed by 150mcg/kg/min infusion, if necessary. May adjust infusion rate as required up to 300mcg/kg/min. Gradual control: Give loading dose infusion of 500mcg/kg/min for 1 minute followed by 4-minute maintenance infusion of 50mcg/kg/min. If an adequate therapeutic effect is not observed within 5 minutes, repeat the same loading dose and follow with a maintenance infusion increased to 100mcg/kg/min.