Blephamide S.o.p. Oint

  • Ocular allergy/inflammation

Blephamide S.o.p. Oint Generic Name & Formulations

General Description

Sulfacetamide sodium 10%, prednisolone acetate 0.2%.

Pharmacological Class

Sulfonamide + steroid.

See Also

How Supplied

Susp—5mL, 10mL; Oint—3.5g


Blephamide S.o.p. Oint Indications


Ocular inflammation with infection.

Blephamide S.o.p. Oint Dosage and Administration

Adults and Children

<6yrs: not established. ≥6yrs: 2 drops every 4 hours and at bedtime or small amount of ointment 3–4 times daily and 1–2 times at night. May prolong dosing interval as condition improves; max 20mL or 8g per therapeutic course. Re-evaluate if no improvement after 2 days.

Blephamide S.o.p. Oint Contraindications


Ocular fungal, viral, or mycobacterial infections.

Blephamide S.o.p. Oint Boxed Warnings

Not Applicable

Blephamide S.o.p. Oint Warnings/Precautions


Corneal or scleral thinning: increased risk of perforation. Glaucoma. Severe dry eye. Purulent exudates may inactivate sulfonamides. Cataract surgery: may delay healing and increase bleb formation. May mask signs of infection. Monitor for secondary ocular infections (eg, fungal) and intraocular pressure in prolonged use (≥10 days). Discontinue if rash or hypersensitivity reactions occur. Avoid abrupt cessation. Pregnancy. Nursing mothers: not recommended.

Blephamide S.o.p. Oint Pharmacokinetics




Renal. Half-life: 7–12.8 hours (sulfacetamide), 2–3 hours (prednisolone).

Blephamide S.o.p. Oint Interactions


Incompatible with silver-containing preparations. Antagonized by PABA.

Blephamide S.o.p. Oint Adverse Reactions

Adverse Reactions

Ocular irritation, secondary ocular infections; rare: severe sulfonamide reactions (eg, Stevens-Johnson syndrome, toxic epidermal necrolysis, fulminant hepatic necrosis, blood dyscrasias). In prolonged use: increased IOP, cataracts, optic nerve damage.

Blephamide S.o.p. Oint Clinical Trials

See Literature

Blephamide S.o.p. Oint Note

Not Applicable

Blephamide S.o.p. Oint Patient Counseling

See Literature