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Bisoprolol Generic Name & Formulations
Legal Class
Rx
General Description
Bisoprolol (as fumarate) 5mg+, 10mg; tabs; +scored.
Pharmacological Class
Cardioselective beta-blocker.
How Supplied
Contact supplier
Manufacturer
Bisoprolol Indications
Indications
Hypertension.
Bisoprolol Dosage and Administration
Adult
5mg once daily; max 20mg once daily. Renal or hepatic impairment, or bronchospastic disease: initially 2.5mg once daily.
Children
Not established.
Bisoprolol Contraindications
Contraindications
Cardiogenic shock. Overt heart failure. 2nd- or 3rd-degree AV block. Marked sinus bradycardia.
Bisoprolol Boxed Warnings
Not Applicable
Bisoprolol Warnings/Precautions
Warnings/Precautions
CHF. Angina. Peripheral vascular disease. Asthma. COPD. Surgery. Diabetes. Thyroid disease. Hepatic or renal impairment. Avoid abrupt cessation. Pregnancy (Cat.C). Nursing mothers.
Bisoprolol Pharmacokinetics
See Literature
Bisoprolol Interactions
Interactions
Additive effects with reserpine, guanethidine, other catecholamine depleting drugs, calcium channel blockers, antiarrhythmics, myocardial depressants. Increased rebound hypertension with clonidine withdrawal. Antagonized by rifampin. May block epinephrine.
Bisoprolol Adverse Reactions
Adverse Reactions
Headache, fatigue, GI upset, upper respiratory symptoms (eg, cough, dyspnea, rhinitis), chest pain.
Bisoprolol Clinical Trials
See Literature
Bisoprolol Note
Notes
Formerly known under the brand name Zebeta.
Bisoprolol Patient Counseling
See Literature
