Endometriosis:
Indications for AYGESTIN:
Endometriosis.
Adult:
Initially 5mg daily for 2 weeks, then increase by 2.5mg/day every 2 weeks up to 15mg/day maintenance dose. Continue for 6–9 months unless breakthrough bleeding is intolerable.
Children:
Not applicable.
Contraindications:
Thromboembolic disorders. Hepatic dysfunction. Undiagnosed vaginal bleeding. Breast or genital carcinoma. Missed abortion. Pregnancy (Cat.X).
Warnings/Precautions:
Cardiac or renal dysfunction. Depression. Include Pap smear in pretreatment exam. Conditions aggravated by fluid retention. Discontinue if jaundice, visual disturbances, migraine, or thrombotic disorders occur. Nursing mothers.
Pharmacologic Class:
Progestin.
Interactions:
Rifampin may increase metabolism.
Adverse Reactions:
Menstrual and cervical changes, edema, jaundice, rash, depression, mastodynia, decreased glucose tolerance, weight changes, thromboembolic disease, breakthrough bleeding, melasma, chloasma.
How Supplied:
Tabs—50
Pricing for AYGESTIN
Menopause and HRT:
Indications for AYGESTIN:
Secondary amenorrhea, abnormal uterine bleeding due to hormonal imbalance without organic pathology.
Adult:
2.5–10mg daily for 5–10 days during 2nd half of theoretical menstrual cycle after estrogens if needed.
Children:
Not applicable.
Contraindications:
Thromboembolic disorders. Hepatic dysfunction. Undiagnosed vaginal bleeding. Breast or genital carcinoma. Missed abortion. Pregnancy (Cat.X).
Warnings/Precautions:
Cardiac or renal dysfunction. Depression. Include Pap smear in pretreatment exam. Conditions aggravated by fluid retention. Discontinue if jaundice, visual disturbances, migraine, or thrombotic disorders occur. Nursing mothers.
Pharmacologic Class:
Progestin.
Interactions:
Rifampin may increase metabolism.
Adverse Reactions:
Menstrual and cervical changes, edema, jaundice, rash, depression, mastodynia, decreased glucose tolerance, weight changes, thromboembolic disease, breakthrough bleeding, melasma, chloasma.
How Supplied:
Tabs—50
