• Benign prostatic hyperplasia/urinary retention

Avodart Generic Name & Formulations

General Description

Dutasteride 0.5mg; caps.

Pharmacological Class

Type I and II 5 alpha-reductase inhibitor.

How Supplied

Caps—30, 90


Generic Availability


Avodart Indications


BPH, as monotherapy to improve symptoms and reduce risks of acute urinary retention and need for prostate surgery; or in combination with tamsulosin. Limitation of use: not approved for preventing prostate cancer.

Avodart Dosage and Administration


Swallow whole. Monotherapy: 0.5mg once daily. Combination therapy: 0.5mg once daily with tamsulosin 0.4mg once daily.


Not indicated.

Avodart Contraindications


Pregnant women.

Avodart Boxed Warnings

Not Applicable

Avodart Warnings/Precautions


Not for use in women. Increased risk of high-grade prostate cancer. Monitor prostate specific antigen (PSA) values (establish new baseline PSA after at least 3months of treatment); double PSA levels to compare with normal values. Rule out prostate cancer and other urological disorders prior to treatment. Hepatic dysfunction. Advise pregnant women to avoid handling caps; may cause potential risk to male fetus. Men should avoid donating blood until at least 6months after last dose.

Avodart Pharmacokinetics

See Literature

Avodart Interactions


May be potentiated by CYP3A4/5 inhibitors (eg, ritonavir, ketoconazole, verapamil, diltiazem, cimetidine, troleandomycin, ciprofloxacin); caution.

Avodart Adverse Reactions

Adverse Reactions

Impotence, decreased libido, ejaculation disorder, gynecomastia, dizziness (with tamsulosin).

Avodart Clinical Trials

See Literature

Avodart Note

Not Applicable

Avodart Patient Counseling

See Literature