Augmentin Es-600 Suspension

  • Bacterial infections

Augmentin Es-600 Suspension Generic Name & Formulations

General Description

Amoxicillin 600mg, clavulanic acid (as potassium) 42.9mg; per 5mL; strawberry cream flavor (may add FLAVORx); contains phenylalanine.

Pharmacological Class

Broad-spectrum penicillin + β-lactamase inhibitor.

How Supplied

Ext-rel tabs—contact supplier; Tabs 875mg—20; Susp 125mg/5mL, 250mg/5mL—75mL, 100mL, 150mL; Chew tabs—contact supplier; Susp ES-600 600mg/5mL—50mL, 75mL, 100mL, 125mL, 150mL, 200mL


Augmentin Es-600 Suspension Indications


Susceptible recurrent or persistent acute otitis media (see full labeling).

Limitations of Use

Not indicated for the treatment of acute otitis media due to S. pneumoniae with penicillin MIC ≥4mcg/mL.

Augmentin Es-600 Suspension Dosage and Administration


Not recommended.


Take with food. Base dose on amoxicillin component. Due to clavulanic acid component, ES-600 is not interchangable with other susp formulations. <3months: not recommended. ≥3months (<40kg): 90mg/kg per day in 2 divided doses every 12 hours for 10 days. ≥40kg: not recommended.

Augmentin Es-600 Suspension Contraindications


History of amoxicillin/clavulanic acid-associated cholestatic jaundice/hepatic dysfunction. Ext-rel: Severe renal impairment (CrCl <30mL/min) or hemodialysis.

Augmentin Es-600 Suspension Boxed Warnings

Not Applicable

Augmentin Es-600 Suspension Warnings/Precautions


Cephalosporin, imipenem, or other allergy: not recommended. Monitor blood, renal, and hepatic function in long-term use. Monitor closely if skin rash develops; discontinue if lesions progress. Hepatic dysfunction. Mononucleosis. Elderly (consider monitoring renal function). Labor & delivery. Pregnancy (Cat.B). Nursing mothers.

Augmentin Es-600 Suspension Pharmacokinetics

See Literature

Augmentin Es-600 Suspension Interactions


May cause false (+) glucose test with Clinitest, Benedict's or Fehling's soln. Probenecid potentiates amoxicillin. May potentiate oral anticoagulants (monitor). May antagonize oral contraceptives.

Augmentin Es-600 Suspension Adverse Reactions

Adverse Reactions

Diarrhea, nausea, abdominal pain, rash, urticaria, vomiting, vaginitis; anaphylaxis, severe cutaneous adverse reactions (eg, SJS, TEN, DRESS, AGEP).

Augmentin Es-600 Suspension Clinical Trials

See Literature

Augmentin Es-600 Suspension Note

Not Applicable

Augmentin Es-600 Suspension Patient Counseling

See Literature