Ativan Generic Name & Formulations
Mechanism of Action
Ativan Dosage and Administration
Ativan Boxed Warnings
Increased risk of drug-related mortality from concomitant use with opioids. Therapy for >4 months. Discontinue if paradoxical reactions occur. Primary depressive disorder or psychosis: not recommended. Suicidal tendencies (monitor). Renal or hepatic impairment. Compromised respiratory function. Seizure disorder. Reevaluate periodically. Monitor blood counts, liver function with long-term use. Assess patient's risk for abuse, misuse, addiction prior to and during therapy. Avoid abrupt cessation. Change dose gradually. Drug or alcohol abuse. Elderly. Debilitated. Neonatal sedation and withdrawal syndrome; monitor neonates exposed during pregnancy or labor. Pregnancy (esp. late stage). Nursing mothers: monitor infants.
Absolute bioavailability: 90%. Peak concentrations in plasma occur in ~2 hours. Peak plasma level (from a 2mg dose): ~20 ng/mL.
Plasma protein bound: ~85%.
Ativan Adverse Reactions
Ativan Clinical Trials
Ativan Patient Counseling