Asmanex Twisthaler Generic Name & Formulations
Mometasone furoate 110mcg/inh, 220mcg/inh; pwd for oral inhalation; with dose counter.
Twisthaler 110mcg (30 inh)—1; 220mcg (30 inh, 60 inh, 120 inh)—1
Asmanex Twisthaler Indications
Maintenance treatment of asthma as prophylactic therapy.
Limitations of Use
Not for relief of acute bronchospasm.
Asmanex Twisthaler Dosage and Administration
Previously on bronchodilators alone or inhaled corticosteroids: initially 220mcg once in the PM; max 440mcg daily (either as 220mcg twice daily or 440mcg once daily). Previously on oral corticosteroids (wean gradually): initially 440mcg twice daily; max 880mcg daily. Rinse mouth after use.
<4yrs: not established. 4–11yrs: 110mcg once in the PM; max 110mcg daily. Rinse mouth after use.
Asmanex Twisthaler Contraindications
Primary treatment of status asthmaticus or acute asthma attacks. Milk protein allergy.
Asmanex Twisthaler Boxed Warnings
Asmanex Twisthaler Warnings/Precautions
Maintain regular regimen. Prescribe a short-acting, inhaled β2-agonist for acute symptoms. Re-evaluate immediately if episodes of asthma not responsive to bronchodilators; may need oral corticosteroid therapy. Immunosuppressed. Untreated infections (eg, fungal, bacterial, viral, parasitic), TB, ocular herpes simplex. If exposed to chickenpox or measles, consider anti-infective prophylactic therapy. Transferring from systemic steroids: taper gradually. If adrenal insufficiency exists following systemic corticosteroids, replacement with inhaled steroids may exacerbate symptoms of adrenal insufficiency (eg, lassitude). May unmask previously suppressed allergic conditions. Monitor for bone mineral density if other osteoporosis risk factors exist; and for growth suppression in children; hypercorticism and HPA axis suppression (if occurs, reduce gradually). Glaucoma, increased intraocular pressure, and cataracts: consider eye evaluation if ocular symptoms develop or in long term use. Severe hepatic impairment. Pregnancy. Nursing mothers.
Asmanex Twisthaler Pharmacokinetics
Asmanex Twisthaler Interactions
Potentiated by ketoconazole or other strong CYP3A4 inhibitors (eg, ritonavir, cobicistat-containing products, atazanavir, clarithromycin, indinavir, itraconazole, nefazodone, nelfinavir, saquinavir, telithromycin); use caution and monitor.
Asmanex Twisthaler Adverse Reactions
Headache, allergic rhinitis, pharyngitis, upper respiratory tract infection, sinusitis, oral candidiasis, dysmenorrhea, musculoskeletal pain, back pain, dyspepsia; hypersensitivity reactions, paradoxical bronchospasm; discontinue if occurs. Children: also fever, bruise.
Asmanex Twisthaler Clinical Trials
Asmanex Twisthaler Note
Asmanex Twisthaler Patient Counseling