Asmanex Twisthaler

  • Asthma/COPD

Asmanex Twisthaler Generic Name & Formulations

General Description

Mometasone furoate 110mcg/inh, 220mcg/inh; pwd for oral inhalation; with dose counter.

Pharmacological Class


How Supplied

Twisthaler 110mcg (30 inh)—1; 220mcg (30 inh, 60 inh, 120 inh)—1


Generic Availability


Asmanex Twisthaler Indications


Maintenance treatment of asthma as prophylactic therapy.

Limitations of Use

Not for relief of acute bronchospasm.

Asmanex Twisthaler Dosage and Administration


Previously on bronchodilators alone or inhaled corticosteroids: initially 220mcg once in the PM; max 440mcg daily (either as 220mcg twice daily or 440mcg once daily). Previously on oral corticosteroids (wean gradually): initially 440mcg twice daily; max 880mcg daily. Rinse mouth after use.


<4yrs: not established. 4–11yrs: 110mcg once in the PM; max 110mcg daily. Rinse mouth after use.

Asmanex Twisthaler Contraindications


Primary treatment of status asthmaticus or acute asthma attacks. Milk protein allergy.

Asmanex Twisthaler Boxed Warnings

Not Applicable

Asmanex Twisthaler Warnings/Precautions


Maintain regular regimen. Prescribe a short-acting, inhaled β2-agonist for acute symptoms. Re-evaluate immediately if episodes of asthma not responsive to bronchodilators; may need oral corticosteroid therapy. Immunosuppressed. Untreated infections (eg, fungal, bacterial, viral, parasitic), TB, ocular herpes simplex. If exposed to chickenpox or measles, consider anti-infective prophylactic therapy. Transferring from systemic steroids: taper gradually. If adrenal insufficiency exists following systemic corticosteroids, replacement with inhaled steroids may exacerbate symptoms of adrenal insufficiency (eg, lassitude). May unmask previously suppressed allergic conditions. Monitor for bone mineral density if other osteoporosis risk factors exist; and for growth suppression in children; hypercorticism and HPA axis suppression (if occurs, reduce gradually). Glaucoma, increased intraocular pressure, and cataracts: consider eye evaluation if ocular symptoms develop or in long term use. Severe hepatic impairment. Pregnancy. Nursing mothers.

Asmanex Twisthaler Pharmacokinetics

See Literature

Asmanex Twisthaler Interactions


Potentiated by ketoconazole or other strong CYP3A4 inhibitors (eg, ritonavir, cobicistat-containing products, atazanavir, clarithromycin, indinavir, itraconazole, nefazodone, nelfinavir, saquinavir, telithromycin); use caution and monitor.

Asmanex Twisthaler Adverse Reactions

Adverse Reactions

Headache, allergic rhinitis, pharyngitis, upper respiratory tract infection, sinusitis, oral candidiasis, dysmenorrhea, musculoskeletal pain, back pain, dyspepsia; hypersensitivity reactions, paradoxical bronchospasm; discontinue if occurs. Children: also fever, bruise.

Asmanex Twisthaler Clinical Trials

See Literature

Asmanex Twisthaler Note

Not Applicable

Asmanex Twisthaler Patient Counseling

See Literature