Ascomp W. Codeine

  • Migraine and headache

Ascomp W. Codeine Generic Name & Formulations

General Description

Codeine phosphate 30mg, butalbital 50mg, aspirin 325mg, caffeine 40mg; caps.

Pharmacological Class

Opioid + barbiturate + salicylate + stimulant.

How Supplied

Caps—100, 500

Ascomp W. Codeine Indications


Tension (or muscle contraction) headache.

Ascomp W. Codeine Dosage and Administration


1–2 caps every 4 hours, as needed; max 6 caps/day. Use lowest effective dose for shortest period of time.


Not recommended.

Ascomp W. Codeine Contraindications


NSAID allergy. Porphyria. Bleeding or coagulation disorders. Peptic ulcer.

Ascomp W. Codeine Boxed Warnings

Not Applicable

Ascomp W. Codeine Warnings/Precautions


Renal or hepatic impairment; monitor liver/renal function tests. Acute abdomen. Asthma. Bleeding disorders. Head injury. Increased intracranial pressure. Impaired thyroid or adrenocortical function. GI or GU obstruction. Ultra-rapid metabolizers of codeine (may experience overdose symptoms). Drug abusers. Elderly. Debilitated. Labor & delivery. Pregnancy (Cat.C). Nursing mothers: not recommended.

Ascomp W. Codeine Pharmacokinetics

See Literature

Ascomp W. Codeine Interactions


CNS effects may be enhanced by MAOIs. Concomitant corticosteroids: withdrawal of corticosteroid may result in salicylism. May potentiate oral anticoagulants, oral antidiabetics and insulin, 6-mercaptopurine and methotrexate, NSAIDs, other narcotic analgesics, alcohol, general anesthetics, tranquilizers, sedative-hypnotics, other CNS depressants. May diminish effects of uricosuric agents.

Ascomp W. Codeine Adverse Reactions

Adverse Reactions

Drowsiness, dizziness, intoxicated feeling, GI upset/pain.

Ascomp W. Codeine Clinical Trials

See Literature

Ascomp W. Codeine Note

Not Applicable

Ascomp W. Codeine Patient Counseling

See Literature