Ascomp W. Codeine Generic Name & Formulations
Codeine phosphate 30mg, butalbital 50mg, aspirin 325mg, caffeine 40mg; caps.
Opioid + barbiturate + salicylate + stimulant.
Ascomp W. Codeine Indications
Tension (or muscle contraction) headache.
Ascomp W. Codeine Dosage and Administration
1–2 caps every 4 hours, as needed; max 6 caps/day. Use lowest effective dose for shortest period of time.
Ascomp W. Codeine Contraindications
NSAID allergy. Porphyria. Bleeding or coagulation disorders. Peptic ulcer.
Ascomp W. Codeine Boxed Warnings
Ascomp W. Codeine Warnings/Precautions
Renal or hepatic impairment; monitor liver/renal function tests. Acute abdomen. Asthma. Bleeding disorders. Head injury. Increased intracranial pressure. Impaired thyroid or adrenocortical function. GI or GU obstruction. Ultra-rapid metabolizers of codeine (may experience overdose symptoms). Drug abusers. Elderly. Debilitated. Labor & delivery. Pregnancy (Cat.C). Nursing mothers: not recommended.
Ascomp W. Codeine Pharmacokinetics
Ascomp W. Codeine Interactions
CNS effects may be enhanced by MAOIs. Concomitant corticosteroids: withdrawal of corticosteroid may result in salicylism. May potentiate oral anticoagulants, oral antidiabetics and insulin, 6-mercaptopurine and methotrexate, NSAIDs, other narcotic analgesics, alcohol, general anesthetics, tranquilizers, sedative-hypnotics, other CNS depressants. May diminish effects of uricosuric agents.
Ascomp W. Codeine Adverse Reactions
Drowsiness, dizziness, intoxicated feeling, GI upset/pain.
Ascomp W. Codeine Clinical Trials
Ascomp W. Codeine Note
Ascomp W. Codeine Patient Counseling