• Nonnarcotic analgesics

Anjeso Generic Name & Formulations

General Description

Meloxicam 30mg/mL; per vial; aqueous dispersion for IV inj; contains sucrose.

Pharmacological Class

NSAID (oxicam).

How Supplied

Single-dose vial—1


Generic Availability


Anjeso Indications


Moderate to severe pain, alone or in combination with non-NSAID analgesics.

Limitations of Use

Not recommended for use when rapid onset of analgesia is required.

Anjeso Dosage and Administration


Use for shortest duration. Individualize. Administer by IV bolus inj over 15secs. 30mg once daily.


Not established.

Anjeso Contraindications


Aspirin allergy. Coronary artery bypass graft surgery. Moderate to severe renal insufficiency at risk for renal failure due to volume depletion.

Anjeso Boxed Warnings

Boxed Warning

Risk of serious cardiovascular and gastrointestinal events.

Anjeso Warnings/Precautions


Increased risk of serious cardiovascular events (including MI, stroke). Avoid in recent MI, severe HF, advanced renal disease; if necessary, monitor. Increased risk of serious GI adverse events (including inflammation, bleeding, ulceration, perforation). History of ulcer disease and/or GI bleeding. Advanced liver disease and/or coagulopathy. Discontinue if signs/symptoms of liver disease develop, or if systemic manifestations (eg, eosinophilia, rash) occur. Hypertension; monitor BP closely. Dehydration. Hypovolemia. Hyperkalemia. Pre-existing asthma. Discontinue at 1st sign of rash or any other hypersensitivity. Coagulation disorders. Monitor CBCs, blood chemistry, hepatic, and renal function in long-term therapy. May mask signs of infection or fever. Severe hepatic impairment: monitor. Moderate to severe renal impairment: not recommended. CYP2C9 poor metabolizers. Elderly. Debilitated. Women with infertility: not recommended. Labor & delivery. Pregnancy (≥30 weeks gestation; avoid). Nursing mothers.

Anjeso Pharmacokinetics

See Literature

Anjeso Interactions


Avoid concomitant aspirin (at analgesic doses), other NSAIDs, or salicylates (eg, diflunisal, salsalate). Increased risk of GI bleed with anticoagulants (eg, warfarin), antiplatelets, oral corticosteroids, SSRIs, SNRIs, smoking, alcohol, or prolonged NSAID therapy; monitor. May antagonize or increase risk of acute renal failure (esp. in elderly, volume-depleted, or have renal impairment) with ACE inhibitors, ARBs, β-blockers, diuretics; monitor. May potentiate lithium, methotrexate, cyclosporine; monitor for toxicity. Concomitant pemetrexed may increase risk of pemetrexed-associated myelosuppression, renal, and GI toxicity. May be potentiated by CYP2C9 inhibitors (eg, amiodarone, fluconazole, sulphaphenazole); monitor and consider dose reduction.

Anjeso Adverse Reactions

Adverse Reactions

Constipation, increased GGT, anemia; elevated ALT/AST, cardiovascular events, GI bleed/ulcer, edema, hyperkalemia, anaphylactic reactions, rash, hepatotoxicity, renal papillary necrosis, acute renal failure.

Anjeso Clinical Trials

See Literature

Anjeso Note

Not Applicable

Anjeso Patient Counseling

See Literature