Amrix Generic Name & Formulations
Cyclobenzaprine HCl 15mg, 30mg; ext-rel caps.
Muscle relaxant (central).
Adjunct to rest and physical therapy for relief of muscle spasm associated with acute, painful musculoskeletal conditions.
Amrix Dosage and Administration
Swallow whole; or may sprinkle contents on applesauce and swallow immediately without chewing. Take at same time each day. 15mg once daily; may increase to 30mg/day given once daily. Max 2–3 weeks.
Acute post-MI. Arrhythmias, heart block, other conduction disturbances. CHF. Hyperthyroidism. During or within 14 days of MAOIs.
Amrix Boxed Warnings
Not effective in treating spasticity associated with cerebral or spinal chord disease or in children with cerebral palsy. Consider discontinuing if significant CNS symptoms develop. Urinary retention. Angle-closure glaucoma. Increased intraocular pressure. Hepatic impairment or elderly: not recommended. Pregnancy. Nursing mothers.
See Contraindications. Hypertensive crisis with MAOIs. Increased risk of serotonin syndrome with other serotonergic drugs (eg, SSRIs, SNRIs, tricyclic antidepressants, tramadol, bupropion, meperidine, verapamil, MAOIs); discontinue if occurs. May potentiate alcohol, barbiturates, other CNS depressants. Caution with anticholinergics. May antagonize guanethidine and similar acting compounds. May enhance seizure risk with concomitant tramadol.
Amrix Adverse Reactions
Dry mouth, dizziness, fatigue, constipation, nausea, dyspepsia, somnolence; serotonin syndrome, cardiovascular effects.
Amrix Clinical Trials
Amrix Patient Counseling