Bacterial infections:

Indications for: Ampicillin Sodium Injection

Ampicillin-sensitive infections.

Adults and Children:

Give IV inj slowly over at least 10–15 minutes; rapid IV administration may result in convulsive seizures. Respiratory tract and soft tissue infections: <40kg: 25–50mg/kg per day in equally divided doses every 6–8 hours. ≥40kg: 250–500mg every 6 hours. GI or GU tract infections (including N. gonorrhoeae in women): <40kg: 50mg/kg per day in equally divided doses every 6–8 hours. ≥40kg: 500mg every 6 hours. Urethritis in males due to N. gonorrhoeae: two doses of 500mg each at interval of 8–12 hours. Meningitis: Initiate with IV drip, then continue IM. 150–200mg/kg per day in equally divided doses every 3–4 hours. Septicimia: Initiate IV for at least 3 days, then continue IM every 3–4 hours. 150–200mg/kg per day; treat for at least 10 days if caused by Group A β-hemolytic streptococci.

Ampicillin Sodium Injection Warnings/Precautions:

Cephalosporin, imipenem, other allergy or mononucleosis: not recommended. Monitor blood, renal, and liver function in long-term use. Pregnancy (Cat.B). Nursing mothers.

Ampicillin Sodium Injection Classification:

Broad-spectrum penicillin.

Ampicillin Sodium Injection Interactions:

May cause false (+) glucose test with Clinitest, Benedict's or Fehling's soln. Potentiated by probenecid. May increase risk of rash with allopurinol.

Adverse Reactions:

Anaphylaxis, urticaria, GI upset, blood dyscrasias.


Formerly known under the brand names Principen, Totacillin, Pfizerpen-A, Penbritin, Omnipen, Amcill (caps, susp); Polycillin-N, Totacillin-N, Penbritin-S, Omnipen-N (inj).

How Supplied:

Contact supplier.