Select therapeutic use:

Parkinsonism:

Indications for: Amantadine

Parkinsonism. Drug-induced extrapyramidal reactions.

Adult Dosage:

Parkinsonism monotherapy: initially 100mg twice daily, may increase after 1–2 weeks by 100mg daily. Serious associated illness or high doses of other antiparkinson drugs: 100mg once daily, may increase after 1 to several weeks to 100mg twice daily; max 400mg/day in divided doses. Extrapyramidal disorders: 100mg twice daily; max 300mg/day in divided doses. Renal dysfunction: reduce dose; see literature.

Children Dosage:

Not recommended.

Amantadine Warnings/Precautions:

Adjust dose gradually. History of seizures. Heart failure. Orthostatic hypotension. Peripheral edema. Renal (CrCl <50mL/min) or hepatic dysfunction. Psychiatric disorders. Suicidal ideation. History of recurrent eczematoid rash. Elderly. Pregnancy (Cat.C). Nursing mothers: not recommended.

See Also:

Amantadine Classification:

Dopamine agonist.

Amantadine Interactions:

Caution with CNS stimulants. Thioridazine may worsen tremor in elderly patients with parkinsonism.

Adverse Reactions:

Neuroleptic malignant syndrome (when drug is withdrawn or dose is reduced), nausea, dizziness, insomnia, heart failure, anxiety, irritability, hallucinations, confusion, anorexia, anticholinergic effects, constipation, ataxia, livedo reticularis, peripheral edema, orthostatic hypotension, headache, somnolence, dream abnormality, diarrhea, fatigue.

Note:

Formerly known under the brand name Symmetrel.

How Supplied:

Contact supplier.

Pricing for Amantadine

100mg tablet (Qty: 60)
Appx. price $39
GoodRx

Viral infections:

Indications for: Amantadine

Prophylaxis and treatment of influenza A infections.

Adult Dosage:

200mg daily in 1–2 divided doses. Elderly: 100mg/day. Renal dysfunction: reduce dose; see literature.

Children Dosage:

<1yr: not recommended. 1–9yrs: 4.4–8.8mg/kg per day; max 150mg daily. 9–12yrs: 100mg twice daily. Renal dysfunction: reduce dose; see literature.

Amantadine Warnings/Precautions:

History of seizures. Heart failure. Orthostatic hypotension. Peripheral edema. Renal (CrCl <50mL/min) or hepatic dysfunction. Psychiatric disorders. Suicidal ideation. History of recurrent eczematoid rash. Elderly. Pregnancy (Cat.C). Nursing mothers: not recommended.

See Also:

Amantadine Classification:

Adamantane.

Amantadine Interactions:

Caution with CNS stimulants.

Adverse Reactions:

Neuroleptic malignant syndrome (when drug is withdrawn or dose is reduced), nausea, dizziness, insomnia, heart failure, anxiety, irritability, hallucinations, confusion, anorexia, anticholinergic effects, constipation, ataxia, livedo reticularis, peripheral edema, orthostatic hypotension, headache, somnolence, dream abnormality, diarrhea, fatigue.

Note:

Formerly known under the brand name Symmetrel.

How Supplied:

Contact supplier.

Pricing for Amantadine

100mg tablet (Qty: 60)
Appx. price $39
GoodRx