• Acne

Aklief Generic Name & Formulations

General Description

Trifarotene 0.005%; crm.

Pharmacological Class


How Supplied

Crm—30g, 45g, 75g

Generic Availability


Aklief Indications


Acne vulgaris.

Aklief Dosage and Administration

Adults and Children

<9yrs: not established. ≥9yrs: apply a thin layer to affected areas once daily in the evening. Face: 1 pump actuation. Upper trunk: 2 pump actuations; may use 1 additional pump actuation for middle and lower back, if needed.

Aklief Contraindications

Not Applicable

Aklief Boxed Warnings

Not Applicable

Aklief Warnings/Precautions


Not for oral, ophthalmic, or intravaginal use. Avoid eyes, lips, paranasal creases, mucous membranes. Do not use on cuts, abrasions, eczematous or sunburned skin. Advise patients to use a moisturizer, reduce frequency, suspend, or discontinue therapy based on severity of skin irritation. Minimize exposure to sun and UV light; if unavoidable, use sunscreen and protective clothing. Pregnancy. Nursing mothers: avoid direct infant exposure.

Aklief Pharmacokinetics

See Literature

Aklief Interactions


Avoid waxing on treated skin areas.

Aklief Adverse Reactions

Adverse Reactions

Application site irritation (erythema, scaling, dryness, stinging/burning), application site pruritus, sunburn.

Aklief Clinical Trials

See Literature

Aklief Note

Not Applicable

Aklief Patient Counseling

See Literature