Obesity:

Indications for ADIPEX-P:

Short-term monotherapy as adjunct in management of exogenous obesity in patients with initial body mass ≥30kg/m2, or ≥27kg/m2 in presence of other risk factors.

Adult:

>16yrs: 37.5mg once daily before or 1–2 hrs after breakfast, or 18.75mg 1–2 times daily. Avoid late evening dosing.

Children:

≤16yrs: not recommended.

Contraindications:

Arteriosclerosis. Cardiovascular disease. Hypertension. Hyperthyroidism. Glaucoma. Agitation. Drug or alcohol abuse. During or within 14 days of MAOIs.

Warnings/Precautions:

Discontinue if dyspnea, angina pectoris, syncope, lower extremity edema or other symptoms of primary pulmonary hypertension occur. Discontinue after a few weeks as tolerance to anorectic effect occurs. Diabetes. Prescribe limited supply to prevent overdose. Pregnancy (Cat.C). Nursing mothers: not recommended.

Pharmacologic Class:

Sympathomimetic.

Interactions:

Hypertensive crisis with MAOIs. Concomitant SSRIs: not recommended. Avoid alcohol. Blocks guanethidine. Monitor antidiabetic agents. Possible risk of valvular heart disease with fenfluramine.

Adverse Reactions:

CNS overstimulation, dizziness, palpitations, arrhythmias, hypertension, psychosis, dry mouth, GI disturbances, urticaria, impotence, primary pulmonary hypertension, and/or regurgitant cardiac valvular disease.

Generic Availability:

YES

How Supplied:

Caps—100; Tabs—100, 1000

Pricing for ADIPEX-P

37.5mg tablet (Qty: 30)
Appx. price $12
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