Acetazolamide Injection

  • Edema

Acetazolamide Injection Generic Name & Formulations

General Description

Acetazolamide 500mg/vial; pwd for inj after reconstitution; preservative-free.

Pharmacological Class

Carbonic anhydrase inhibitor.

How Supplied

Contact supplier.

Acetazolamide Injection Indications



Acetazolamide Injection Dosage and Administration


Give by IV inj. Edema: give 1–2 days on, 1 day off. 250mg–375mg once daily. CHF: 250–375mg once daily in the AM. Acute high altitude sickness: see literature.


Not recommended.

Acetazolamide Injection Contraindications


Hypokalemia. Hyponatremia. Severe renal, hepatic, or adrenocortical impairment. Hyperchloremic acidosis. Cirrhosis. Chronic noncongestive angle-closure glaucoma. Sulfonamide allergy.

Acetazolamide Injection Boxed Warnings

Not Applicable

Acetazolamide Injection Warnings/Precautions


Respiratory impairment. Renal calcium calculi. Diabetes. Gout. Monitor blood and electrolytes. Elderly. Pregnancy (Cat.C). Nursing mothers: not recommended.

Acetazolamide Injection Pharmacokinetics

See Literature

Acetazolamide Injection Interactions


Inhibits renal excretion of basic drugs and promotes excretion of acidic drugs. May increase toxicity of salicylates (acidosis), folic acid antagonists. Hypokalemia with corticosteroids, potassium wasting diuretics. Monitor phenytoin, primidone, antihyperglycemics, quinidine, lithium, cyclosporine. Antagonizes methenamine.

Acetazolamide Injection Adverse Reactions

Adverse Reactions

Anorexia, drowsiness, confusion, malaise, depression, GI distress, paresthesias, tinnitus, acidosis, initial hypokalemia, hyperuricemia, transient myopia; renal calculi, nephrotoxicity, hepatic dysfunction, blood dyscrasias, rash, fever, photosensitivity (rare).

Acetazolamide Injection Clinical Trials

See Literature

Acetazolamide Injection Note


Formerly known under the brand name Diamox.

Acetazolamide Injection Patient Counseling

See Literature