Diagnostic Agents

Post-Endoscopic Infection More Common Than Previously Thought

June 22, 2018

The rates of infections were compared with those after screening mammography, prostate cancer screening, bronchoscopy, and cystoscopy procedures.

AAFP Still Recommends CRC Screening From Age 50 to 75

June 21, 2018

The AAFP agrees with the USPSTF recommendation for screening patients at ages 50 to 75 years, and graded its recommendation B.

Cleared Blood Glucose Monitor Systems Not Always Accurate

June 19, 2018

"Cleared BGMs do not always meet the level of analytical accuracy currently required for regulatory clearance," the authors write.

USPSTF: No to ECG Screening to Prevent CVD in Low-Risk Adults

June 13, 2018

The researchers found that it is very unlikely that the information from resting or exercise ECG would result in a change in a patient's risk category that would lead to a change in treatment or improve health outcomes for asymptomatic adults at low risk for CVD events.

New Coagulation Monitoring Device Allows for Wireless Reporting of INR Results

By June 11, 2018

The system is intended for properly selected trained users ≥22 years of age who have been stabilized on anticoagulation with vitamin K antagonists for ≥6 weeks.

ASCO: New Assays May Detect Early Lung Cancer in Blood

June 06, 2018

The researchers found that more than 50% of the 3,055 nonsynonymous mutations detected across 122 evaluable patients with lung cancer were detected in WBC consistent with clonal hematopoiesis.

Should Genealogy Data Be Used for Criminal Justice Purposes?

By May 30, 2018

Informed consent, privacy, and justice concerns are 3 issues that should be addressed before the use of online genealogy data in criminal cases becomes widely adopted.

Extended INR Test Intervals Safe for Warfarin-Treated Patients

May 23, 2018

Similar number of out-of-range next INR values for patients with, without extended testing interval

FDA: New Med Guide for Patients Receiving Gadolinium-Based Contrast Agents

By May 17, 2018

These Medication Guides should be provided the first time an outpatient receives a GBCA injection at an MRI center; hospital patients are not required to receive a Medication Guide.

First Test to ID <i>Candida auris</i> Gets FDA Approval

By April 23, 2018

The Bruker Maldi system is already cleared for use in identifying 333 species or species groups, including 424 bacteria and yeast species.

FDA Approves Unique Device for Diabetic Retinopathy Screening

By April 11, 2018

This is the first device authorized for marketing that provides a screening decision without the need for clinician interpretation.

Few Indoor Tanners Have Been Screened for Skin Cancer

April 05, 2018

"Few indoor tanners (ITs) have been screened for skin cancer, although skin cancer (SC) rates are higher than among non-tanners," the authors write. "It is not surprising that SC screening is associated with SC risk factors (e.g., family history of SC and age) among ITs."

Non-Targeted HIV Testing in ER Acceptable to Patients

March 29, 2018

The researchers found that 2,355 of the 9,583 patients (24.6%) who presented to the emergency department during the study period were approached by the HIV counseling and testing staff; 72.8% of patients accepted testing.

First Tests to Screen for Babesiosis in Whole Blood, Plasma Approved

By March 07, 2018

These tests are intended to screen samples from individual human donors, including volunteers who give whole blood and blood components, as well as living organ and tissue donors.

FDA Authorizes First Direct-to-Consumer BRCA Mutation Test

By March 06, 2018

According to a National Cancer Institute study about 2% of Ashkenazi Jewish women carry 1 of the hereditary mutations the test can detect. Among other ethnic populations this occurrence is only 0% to 0.1%.

Early dermatology consultation linked to improved diagnostic accuracy and care in cellulitis

February 28, 2018

Among patients admitted to the hospital for a provisional diagnosis of cellulitis, early dermatologic consultation was associated with improved recognition of pseudo-cellulitis, decreased antibiotic use, and earlier discharge.

Dermoscopic Criteria Accuracy Assessed in Diagnosing Melanoma in Situ

February 23, 2018

The researchers found that 25.3% of the lesions were MIS. The most frequent dermoscopic criteria for MIS were regression, atypical network, and irregular dots and/or globules (92.9, 85.5, and 50.2%, respectively).

Kurtosis Diffusion-Weighted Imaging May Reduce False Positive Mammographies

February 23, 2018

At the predefined sensitivity of greater than 98.0%, the researchers found that the radiomics feature model reduced false-positive results from 66 to 20 in the independent test set (specificity, 70.0%); BI-RADS 4a and 4b lesions benefited from the analysis (74.0 and 60.0%, respectively).

New Test May Help Diagnose Autism Earlier in Children

By February 20, 2018

In this study, researchers explored the association of proteotoxic damage with autism spectrum disorder.

First Blood Test to Assess Concussion in Adults Gets FDA Approval

By February 15, 2018

Banyan BTI (Brain Trauma Indicator) is an in vitro diagnostic blood test to aid in the evaluation of patients with suspected TBI.

FDA: New Clinical Decision Support Tool Helps ID Stroke Sooner

By February 14, 2018

The Viz.AI Contact application is a computer-aided triage software that uses an artificial intelligence algorithm to analyze images for indicators associated with a stroke.

FDA: 'Groundbreaking' Approval Enables Domestic Supply of Critical Medical Isotope

February 09, 2018

New technology approved to produce the country's own supply of the radioisotope Technetium-99m

Risk of Appendicitis Measured Following Colonoscopy

January 31, 2018

More frequent codes for appendicitis, appendectomy in week after colonoscopy versus next 51 weeks. This result was not affected by age subgrouping, and there was no increase in appendicitis in weeks two to four.

FDA Expands Pediatric Age Range for MultiHance Contrast Agent

By January 30, 2018

The FDA's approval was supported by data specifically gathered in patients aged <2 years. The 0.1mmol/kg dose significantly improved the visualization and morphologic assessment of CNS lesions as seen in older pediatric patients and adults.

Specific White Matter Patterns Linked to Youth Psychopathology

January 29, 2018

The feature most associated with both of these traits was a brain white matter pattern reflecting frontotemporal connectivity and crossing fibers in the uncinate fasciculus.

MRI Diagnostic for Differentiating Low-Grade Bladder Cancers

January 29, 2018

Across studies, the pooled sensitivity of MR imaging was 0.90 and the specificity was 0.88 for differentiating tumors staged T1 or lower from those staged T2 or higher.

Personalized Genetic Test May Estimate Age of Prostate CA Diagnosis

January 12, 2018

"Polygenic hazard scores can be used for personalized genetic risk estimates that can predict for age at onset of aggressive PCa," the authors write.

FDA Clears UriVarx Test Strips for UTI Detection

By January 11, 2018

The supplements are intended to reduce urinary urgency, accidents, and day/night frequency in patients with overactive bladder and urinary infections.

Delta CHA<sub>2</sub>DS<sub>2</sub>-VASc May Forecast Stroke Likelihood More Accurately

January 09, 2018

The Delta CHA2DS2-VASc score significantly better predicted ischemic stroke compared to baseline or follow-up CHA2DS2-VASc scores