Ertugliflozin Beneficial for Patients With Inadequately Controlled T2DM

February 20, 2018

The researchers found that the mean change in glycated hemoglobin (HbA1c) from baseline to week 52 was −0.9 and −1% in the ertugliflozin 5- and 15-mg groups, respectively; the proportion of patients with HbA1c <7% was 25.6 and 28.5%, respectively, at week 52

Sudden Cardiac Arrest, Ventricular Arrhythmia Risk Examined With Sulfonylureas

By February 16, 2018

Using U.S. Medicaid claims (1999-2010) from 5 states, the researchers sought to examine the association between individual sulfonylureas (glyburide, glimepiride, glipizide) and outpatient-originating SCA/VA; glipizide exposure was considered the reference exposure.

Ready-to-Use Rescue Pen for Severe Hypoglycemia Moves Closer to Approval

By February 16, 2018

The full findings of the trials will not be released until later this year however the Company stated that the trials were a success, with the data already shared with the FDA in a pre-New Drug Application (NDA) meeting.

Factors Leading to Diabetes May Be Identified 20 Years Before Diagnosis

February 12, 2018

A total of 28,244 new T2D cases were identified over the study period, yielding an average 20-year risk of 8.1%. Overweight and obese subjects and those with elevated fasting glucose (fGlu) and triglycerides (TG) had a substantially increased risk among both men and women.

Ozempic, Fiasp Now Available for the Treatment of Diabetes

By February 05, 2018

Both medications received approval from the FDA in 2017.

Improved islet encapsulation device for the treatment of type 1 diabetes

February 05, 2018

A device for islet transplantation for type 1 diabetes was designed and demonstrated to be safe and retrievable in animal models.

Semaglutide Goes Head-to-Head With Dulaglutide in Type 2 Diabetes Trial

By February 01, 2018

The overall safety profiles of semaglutide and dulaglutide were similar in SUSTAIN 7.

Disordered Eating Behavior Linked to Higher HbA1c in Type 1 Diabetes

January 31, 2018

Youth with DEBs had poor glycemic control at baseline that persisted through study. A significant DEB × time interaction effect was seen for mean sensor glucose (P=0.05) and percent sensor glucose values >180mg/dL (P=0.04).

Diet Soda Independently Linked to Higher Diabetic Retinopathy Risk

January 30, 2018

Compared to those with no diet soft drink consumption, there was an independent association between high diet soft drink consumption and increased likelihood of having PDR (odds ratio, 2.51).

Glucagon May Not be Fully Utilized in Prehospital, Emergency Settings

January 30, 2018

Noting that there are 198,200 providers of basic emergency medicine compared with 61,121 paramedics (who are the only members of EMS who carry and administer glucagon), 3 out of 4 times the dispatched responder may be unable to treat hypoglycemia with glucagon.

Update Regarding Tanzeum Injection Availability

By January 26, 2018

The initial decision to discontinue Tanzeum was announced in August 2017 due to limited prescribing of the drug.

Occupational Therapy Beneficial for Young Adults With Diabetes

January 26, 2018

The effect was not modified significantly by sex, ethnicity, diabetes type, recruitment site, or socioeconomic status.

Patients With Diabetes May Be at Increased Risk for Serious Infection

January 24, 2018

Findings demonstrate an important population burden, including hospitalization and death

NovoFine 30G 8mm Pen Needle Will Soon Be Unavailable

By January 22, 2018

The NovoFine Plus 32G 4mm is recommended in its place for appropriate patients.

Growth hormone releasing hormone (GHRH) agonists protect against diabetic retinopathy in animal model

January 19, 2018

GHRH and GHRH receptor levels are decreased in diabetic rats and humans.

Noninvasive Marker May ID Severity of Diabetic Retinopathy

January 18, 2018

"Further longitudinal studies seem warranted to determine whether DRIL is a clinically relevant noninvasive morphological marker in eyes with DME," the authors write.

Bydureon BCise Now Available for the Treatment of Type 2 Diabetes

By January 10, 2018

Bydrueon BCise is indicated as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus.

Unstable Housing Correlated to Increase in Diabetes-Related ER Visits

January 10, 2018

The researchers found that 13.7% of participants reported a diabetes-related emergency department visit or hospitalization in the previous 12 months.

Bidirectional Links Between Depression, Severe Dysglycemia Evaluated in T1D

January 05, 2018

Depression was strongly associated with increased risk of severe hyperglycemic and hypoglycemic events.

Experts Weigh In on the Best Diets for 2018

By January 03, 2018

DASH and the Mediterranean diet also tied for top stop in the 'Best Diets for Healthy Eating' category will DASH ranked number 1 for the 'Best Heart-Healthy Diets'.

Safety, Tolerability of Dasiglucagon Examined for Severe Hypoglycemia

January 03, 2018

Early pharmacodynamic response for Dasiglucagon were similar to that of GlucaGen, with longer lasting effects plasma glucose.

Microneedle Based Extendin-4 Device Shows Potential for T2D

January 03, 2018

The mechanical strength of alginate-based MN can be enhanced by integration of mineralized particles by crosslinking to facilitate skin penetration.

Three New Type 2 Diabetes Treatments Get FDA Approval

By December 26, 2017

Steglatro, Steglujan, and Segluromet have all received FDA approval for the treatment of type 2 diabetes.

Pre-Op Liraglutide Examined for Glucose Lowering in Non-Cardiac Sx

December 19, 2017

Liraglutide group had lower median plasma glucose 1 hour postoperatively compared with the insulin infusion and insulin bolus groups.

Microbiome Intervention by Delayed-Release Niacin May Benefit in T2DM

December 18, 2017

"Targeted microbiome intervention by delayed-release NA might represent a future therapeutic option for prediabetes and type 2 diabetes," the authors write.

Can Pharmacist Care in Medical Homes Improve Patient Goals?

December 15, 2017

Researchers found that, compared with the reference group, CPSS patients were 93% more likely to achieve a blood pressure goal <140/90 mm Hg, 57% more likely to achieve hemoglobin A1c values <8%, and 87% more likely to achieve both disease management goals.

'Smart' Insulin Pen System for Humalog, Novolog Available

By December 14, 2017

The InPen is for use with U-100 Lilly Humalog and Novo Nordisk Novolog rapid-acting insulin and indicated for persons aged 12 years and older.

Optimal Glycemic Targets Examined for Short-Term Intensive Insulin Tx

December 14, 2017

Patients in the middle and lower mean blood glucose tertiles had higher 1-year remission rates versus the upper tertile (68.7 and 75% versus 32.3%; both P<0.001).

First Short-Acting Insulin Approved as a "Follow-On" Product

By December 11, 2017

The use of abbreviated pathways can reduce drug development costs so products can be offered at a lower price to patients.

Following Gastric Bypass, Nature of &#946;-Cell Sensitivity May Change

December 11, 2017

During the highest dose of glucose infusion, the GB subjects had relative hyperglycemia associated with significantly reduced β-cell glucose sensitivity throughout both step-up