Dermatological Disorders

Dupilumab Beneficial in Adolescent Patients With Moderate-to-Severe Atopic Dermatitis

By September 18, 2018

The Phase 3 trial enrolled 251 patients aged 12-17 years old with moderate-to-severe atopic dermatitis, whose disease was not adequately controlled by prescription topical medications or for whom topical treatment was medically inadvisable.

Adalimumab Biosimilar Demonstrates Clinical Equivalence in Psoriasis Study

By September 13, 2018

The Phase 3 study (N=318) enrolled patients aged 18 to 78 years with moderate-to-severe chronic plaque psoriasis who had not previously received treatment with ≥1 biologic.

Novel Treatment for Pemphigus Granted Orphan Drug Designation

By September 13, 2018

Preliminary results from a Phase 1b proof-of-concept study showed that SYNT001 was associated with clinical improvement (as measured by Pemphigus Disease Area Index score) and induced a rapid reduction in lgG and circulating immune complex levels.

CAM Therapies and Psoriasis: Which Treatments Are Effective?

By September 11, 2018

To investigate the effectiveness of CAM modalities in the treatment of plaque psoriasis, researchers searched several databases to identify studies where CAM was used as an intervention.

Patient's Black Hairy Tongue Linked to Antibiotic Therapy

By September 10, 2018

The case involved a 55-year-old female patient who had been admitted to the hospital after suffering injuries from a car accident.

Oral JAK3 Inhibitor Granted Breakthrough Tx Designation for Alopecia Areata

By September 05, 2018

PF-06651600 is an investigational oral Janus kinase 3 (JAK3) inhibitor that is being evaluated in a Phase 2 study which will assess the treatment based on changes from baseline in Severity of Alopecia Tool (SALT) score.

Gene Therapy for Localized Scleroderma Gets FDA's Fast Track Designation

By September 05, 2018

Clinical enrollment for an open-label, single-arm Phase 1/2 trial of FCX-013 was initiated in August 2018.

Resubmitted Duobrii Lotion NDA for Plaque Psoriasis Accepted

By August 30, 2018

Its long-term safety was evaluated in a phase 3, multicenter, open-label study of 555 adults with moderate to severe plaque psoriasis.

FDA Accepts Resubmitted BLA for Injection to Improve Frown Lines

By August 30, 2018

The Company is seeking approval for the treatment to temporarily improve the appearance of moderate to severe glabellar lines.

Psoriasis Treatments

August 29, 2018

Systemic therapy treatment chart for psoriasis patients generally reserved for those with chronic plaque psoriasis without psoriatic arthritis who are candidates for systemic treatment when UV therapy is not available.

Altreno Approved for the Topical Treatment of Acne Vulgaris

By August 24, 2018

The approval was based on 2 double-blind clinical trials involving 1640 patients 9 years of age and older with moderate to severe acne vulgaris.

Iclaprim Gets Priority Review for Acute Bacterial Skin/Skin Structure Infections

By August 15, 2018

Clinical data has indicated that the drug exhibits a low propensity for resistance development as well as a favorable tolerability profile.

Gene Therapy Gets Orphan Drug Designation for Severe Genetic Skin Disease

By August 13, 2018

Patients with TGM-1 deficiency may have chronic pronounced scaling of the skin with increased transepidermal water loss, as the TGM-1 enzyme is essential for facilitating the formation of the epidermal barrier, which prevents dehydration.

Omadacycline Gets FDA Committee Nod for Skin Infections, Pneumonia

By August 09, 2018

The Committee's recommendation was based on data from the omadacycline global development program that included nearly 2000 adults in three Phase 3 studies.

Inverse Link for Mediterranean Diet Score, Severe Psoriasis

August 08, 2018

"If these findings are confirmed, adherence to a Mediterranean diet should be integrated into the routine management of moderate to severe psoriasis," the authors write.

Topical Steroid Potencies

August 07, 2018

Topical steroid classification chart sorted by potency.

Lice and Scabies Treatments

August 07, 2018

Lice and scabies treatment chart, including pediculicides, scabicides, and lice and nit removal aids.

Skin Appears to Be Key Pathway for Absorption of BBQ Fumes

August 06, 2018

"In the case of BBQ fumes, dermal absorption was a more important pathway for intake of low-molecular-weight PAHs than inhalation," the authors write.

Teen Boy Suffers Serious Burns After 'Hot Water Challenge'

July 31, 2018

Clark spent a week in the hospital. His doctors are hopeful that pigment will return in Clark's face within a few months.

Wound Care Products

July 24, 2018

Wound care dressings and cleansers including hydrocolloid occlusive dressings, wet-to-dry dressings, hydrogels, foam dressings, odor-controlling dressings, and xerogels.

Atopic Dermatitis Places Heavy Burden on Patients

July 20, 2018

Adults with AD reported higher proportions of having only fair/poor overall health, being somewhat/very dissatisfied with life, having lower weighted mean Short-Form 12 (SF-12) mental and physical health subscores, and having higher Dermatology Life Quality Index scores, compared to adults without AD.

Fish Pedicure Causes Woman to Lose Toenails

July 16, 2018

Dermatologists should be aware of potential skin, nail problems tied to fish pedicures

Topical JAK Inhibitor Granted Fast Track Designation for Alopecia Areata

By July 09, 2018

ATI-502 is a topical Janus Kinase (JAK) 1/3 inhibitor.

High Patient Burden With Moderate-to-Severe Atopic Dermatitis

July 06, 2018

Many patients with moderate/severe atopic dermatitis have inadequate disease control

Novel Treatment for Primary Axillary Hyperhidrosis Gets FDA Approval

By June 29, 2018

The approval was supported by Phase 3 data from the ATMOS-1 and ATMOS-2 trials which evaluated the absolute change from baseline in sweat production after treatment with Qbrexza, and the proportion of patients who achieved ≥4-point improvement from baseline in their sweating severity (as measured by the Axillary Sweating Daily Diary [ASDD]).

Idaho Pharmacists Able to Prescribe Meds for Several Conditions on July 1

By June 27, 2018

The new rule allows pharmacists to prescribe medications for cold sores, seasonal influenza, strep throat, and urinary tract infections, as well as statins for patients with diabetes.

Oral Acne Treatments

June 26, 2018

Oral medications for the treatment of acne including dosing for antibiotics, retinoids, and contraceptives.

Topical Acne Treatments

June 26, 2018

A chart of topical acne medications for the use in children and adults including available strengths.

Treatment for Necrobiosis Lipoidica Gets Orphan Drug Designation

By June 22, 2018

In a press release Dr. David Young, CEO of Processa said "We plan to begin our clinical studies in 2018 and to accelerate the development of PCS499 in order to provide clinical benefit to [necrobiosis lipoidica] patients as soon as possible."

Treatment of Hidradenitis Suppurativa with SAPHO Syndrome: A Case Review

By June 21, 2018

The male patient presented in 2009 with a "3-year history of multiple interconnecting comedones in the axilla and inguinal regions, as well as scarring from previous lesions."