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Lung surfactants/mucolytics
Only 4 drugs may be compared at once

Generic Name and Formulations:

Poractant alfa (as phospholipids 80mg/mL and proteins 1mg/mL); susp for intratracheal administration; preservative-free.


Chiesi USA, Inc.

Select therapeutic use:

Indications for CUROSURF:

Treatment ("rescue") of respiratory distress syndrome (RDS) in premature infants.


Not applicable.


See literature. Give by intratracheal administration through an endotracheal tube. Each dose should be administered as 2 aliquots. Inital dose of 2.5mL/kg birth weight; may give 2 more doses of 1.25mL/kg birth weight at 12-hour intervals.


Interrupt dosing if reflux of product into endotracheal tube, cyanosis, bradycardia, airway obstruction, hypoventilation, or endotracheal tube dislodgement occurs; treat; resume after stabilization. Monitor respiratory status and clinical condition frequently and carefully.

Pharmacological Class:

Lung surfactant.

Adverse Reactions:

Bradycardia, hypotension, reflux of surfactant into endotracheal tube, others.

How Supplied:

Single-use vials (1.5mL, 3mL)—1