Corticosteroid-responsive Disorders

Steroid Injection Recalled Due to Impurity Results

By March 06, 2018

Sagent announced a voluntary recall of 10 lots of Methylprednisolone Sodium Succinate for Injection in 40mg, 125mg, and 1g strengths.

Availability of Decadron Tablets Announced

By February 16, 2018

Decadron is a first-generation adrenocortical steroid.

Generic Equivalent to Kenalog-40 Injection Now Available

By December 12, 2017

Amneal's triamcinolone acetonide is currently the only AP-rated generic equivalent injectable suspension available.

Serious Adverse Events Linked to Short-Term Corticosteroid Use

By April 13, 2017

The data revealed the most common indications for short-term corticosteroid use to be upper respiratory tract infections, spinal conditions, and allergies.

Does Early Hydrocortisone Tx Impair Neurodevelopment in Preemies?

April 05, 2017

No statistically significant difference in neurodevelopment at 2 with hydrocortisone, placebo

Glucocorticoid Inj Permanently Discontinued

By August 31, 2016

The Food and Drug Administration (FDA) is informing about the permanent discontinuation of Aristospan (triamcinolone hexacetonide injectable suspension; Sandoz).

Drug Interaction Leads to Subtherapeutic Treatment for Patient with Fungal Brain Abscess

By June 22, 2016

Using the Drug Interaction Probability Scale this interaction scored a 7 out of 10 indicating probable interaction.

Glucocorticoid Use May Up Risk of This Infection

June 10, 2016

Community-acquired Staphylococcus aureus bacteremia risk rose along with the dosage

Corticosteroid Injection Currently in Shortage

By March 11, 2016

The FDA is reporting a shortage in certain presentations of Solu-Medrol Powder for Injection (Pfizer) and the generic Methylprednisolone sodium succinate for injection (Fresenius Kabi).

Do Corticosteroids Enhance Coagulation?

January 26, 2016

Ten days of treatment linked to increase in peak thrombin, velocity index, PAI-1, and vWF

Don't Postpone Tx, Say New Addison's Disease Practice Guidelines

By January 13, 2016

The Endocrine Society has issued a new Clinical Practice Guideline (CPG) on diagnosis and treatment of primary adrenal insufficiency or Addison's disease.

Study: High Sugar Consumption May Relieve Stress

By April 16, 2015

Consumption of sugar-sweetened beverages - but not beverages sweetened with aspartame - is associated with suppression of cortisol and stress responses in the brain in new research published in the Journal of Clinical Endocrinology & Metabolism.

Mylan Launches Generic Orapred ODT

December 11, 2014

Mylan announced the launch of Prednisolone Sodium Phosphate Orally Disintegrating Tablets, the generic of Shionogi's Orapred ODT.

FDA Advisory Panel Votes on Epidural Steroid Shots for Pain

November 26, 2014

Experts express concern regarding transforaminal cervical injections with particulate steroids

Upper GI Bleeding Risk Varies for Drug Combos

October 09, 2014

Concomitant use of nonsteroidal anti-inflammatory drugs (NSAIDs), low-dose aspirin or cyclooxygenase-2 (COX-2) selective inhibitors with other drugs can increase the risk of upper gastrointestinal bleeding (UGIB), and the magnitude of interaction varies according to drug combination.

The Neuropsychiatric Effects of Glucocorticoid Therapy

October 01, 2014

Glucocorticoids are commonly prescribed for immune system suppression and to decrease inflammation for a range of medical conditions, but they may also carry a risk of severe adverse neuropsychiatric effects.

Pharmacist Arrested in Fungal Meningitis Outbreak Case

September 05, 2014

The Boston division of the Federal Bureau of Investigation (FBI) has announced the arrest of a former supervising pharmacist at the New England Compounding Center (NECC) on one count of mail fraud related to a nationwide fungal meningitis outbreak.

Cortisol Response and Crash Risk in Teen Drivers

April 10, 2014

Cortisol level in response to stress is associated with crash risk in teenaged drivers.

Anti-Inflammatory Benefits for CKD with Walking

April 04, 2014

Exercise may be an effective anti-inflammatory therapy in pre-dialysis patients with chronic kidney disease.

Globulin Tied to Gestational Diabetes Risk

March 05, 2014

Low prepregnancy sex hormone-binding globulin (SHBG) concentrations correlate with increased risk of gestational diabetes mellitus.

Rare Cushing's Syndrome Mutation Identified

February 27, 2014

Researchers have discovered a genetic mutation that appears to contribute to a rare but severe form of Cushing's syndrome.

Blunted Diurnal Cortisol Pattern and Frailty in the Elderly

February 26, 2014

In older adults, blunted diurnal cortisol patterns are associated with frailty.

Stress Response, Risk Aversion & Market Instability

February 19, 2014

The stress response in traders is associated with greater risk aversion during periods of market volatility, which may contribute to market instability.

Study IDs Cardiovascular Risk for 'Silent' Adrenal Tumors

January 30, 2014

Patients with adrenal tumors of intermediate phenotype or subclinical Cushing's syndrome are at increased risk of cardiovascular events and mortality compared to those with stable non-secreting adrenal incidentalomas.

Methylprednisolone Shot-Linked Fungal Infections Investigated

October 24, 2013

For patients with CNS infections, there was a significant correlation between strokes and increased severity of abnormalities in cerebrospinal fluid.

More Steroid Courses No Better in Preventing Preterm Birth

October 15, 2013

Compared with a single course of antenatal corticosteroid therapy, multiple courses do not increase or decrease the risk of death or disability for the child at age 5 years.

Performance Enhancing Drug Use Common in Young Males

October 14, 2013

Many male youths are using appearance and performance enhancing drugs, which include anabolic steroids and human growth hormone, and are finding them easily accessible online.

Topical Corticosteroid Use in Pregnancy Reassuring

September 09, 2013

Topical maternal exposure to corticosteroids during pregnancy is not associated with orofacial cleft, preterm delivery, fetal death, low Apgar score, and mode of delivery.

Dexamethasone Beats Placebo for Cancer-Related Fatigue

August 02, 2013

Researchers found that dexamethasone is better than placebo for reducing cancer-related fatigue (CRF) in patients with advanced cancer.