ADHD Treatments

ADHD TREATMENTS
Generic	Brand		Strength	Form	Max Dose	Administration
amphetamine	Adzenys ER	CII	1.25mg/mL	ext-rel oral susp	6-12yrs: 18.8mg (15mL) daily 13–17yrs: 12.5mg (10mL) daily	• Give once daily in the AM • May increase by 3.1mg (2.5mL) or 6.3mg (5mL) at weekly intervals
	Adzenys XR-ODT	CII	3.1mg, 6.3mg, 9.4mg, 12.5mg, 15.7mg, 18.8mg	ext-rel orally disintegrating tabs	6–12yrs: 18.8mg/day 13–17yrs: 12.5mg/day	• Give once daily in the AM • May increase by 3.1mg or 6.3mg at weekly intervals
	Dyanavel XR	CII	2.5mg/mL	ext-rel oral susp	≥6yrs: max 20mg/day	• Give once daily in the AM • May increase by 2.5–10mg/day every 4–7 days
amphetamine sulfate	Evekeo	CII	5mg, 10mg	tabs	3–5yrs: initially 2.5mg daily, may increase by 2.5mg/day at weekly intervals ≥6yrs: max 40mg/day	• Avoid late evening doses • Give first dose upon awakening and additional doses at 4−6hr intervals
amphetamine sulfate	Evekeo ODT	CII	5mg, 10mg, 15mg, 20mg	tabs	6-17yrs: 40mg/day	• Give first dose once or twice daily and additional dose after 4–6hrs • Titrate in increments of 5mg at weekly intervals
atomoxetine HCl	Strattera	Rx	10mg, 18mg, 25mg, 40mg, 60mg, 80mg, 100mg	caps	≥6yrs: 1.4mg/kg or 100mg/ day (which– ever is less)	• Swallow whole • Give once daily in the AM or in 2 divided doses (in AM + the late afternoon/ early PM) • May discontinue without tapering dose
clonidine HCl	Kapvay	Rx	0.1mg	ext-rel tabs	6–17yrs: 0.2mg twice daily	• Swallow whole • Titrate by response • Withdraw gradually by 0.1mg/day at 3−7 day intervals
dextro– amphetamine sulfate	—	CII	5mg, 10mg	scored tabs	usually 40mg/day in 2−3 divided doses	• Give in the AM and then 1−2 more doses 4−6hrs apart
	Dexedrine Spansule	CII	5mg, 10mg, 15mg	sust-rel caps	6–17yrs: 40mg/day	• Avoid late evening doses
	Zenzedi	CII	2.5mg, 5mg, 7.5mg, 10mg, 15mg, 20mg, 30mg	tabs	≥3yrs: usually 40mg/day in 2–3 divided doses	• Give first dose upon awakening and then 1–2 more doses 4–6hrs apart • Avoid late evening doses
dexmethyl– phenidate HCl	Focalin	CII	2.5mg, 5mg, 10mg	tabs	≥6yrs: 20mg/day	• Give twice daily at least 4hrs apart • Single isomer methylphenidate product (use 1/2 of racemic methylphenidate dose initially)
dexmethyl– phenidate HCl	Focalin XR	CII	5mg, 10mg, 15mg, 20mg, 25mg, 30mg, 35mg, 40mg	ext-rel caps	6–17yrs: 30mg/day ≥18yrs: 40mg/day	• Give once daily in the AM • May sprinkle contents on applesauce and swallow without chewing beads
guanfacine	Intuniv	Rx	1mg, 2mg, 3mg, 4mg	ext-rel tabs	6–12yrs: 4mg/day 13–17yrs: 7mg/day	• Swallow whole with water, milk, or other liquid • Do not give with high‑fat meals • Withdraw gradually by 1mg every 3−7days
lisdexam– fetamine dimesylate	Vyvanse	CII	10mg, 20mg, 30mg, 40mg, 50mg, 60mg, 70mg (caps only)	caps, chew tabs	≥6yrs: 70mg/day	• Give once daily in the AM. Do not subdivide a single dose. • Caps: swallow whole or may open and mix/dissolve contents in yogurt, water, or orange juice; take immediately • Chew tabs: chew thoroughly before swallowing
metham– phetamine HCl	Desoxyn	CII	5mg	tabs	≥6yrs: usually 20−25mg daily in two divided doses	• Give once or twice daily 30min before meals • May increase at weekly intervals
methylphen– idate	Cotempla XR-ODT	CII	8.6mg, 17.3mg, 25.9mg	ext-rel orally disintegrating tabs	6–17yrs: 51.8mg/day	• Give once daily in the AM • Place on tongue and allow to disintegrate • May titrate in increments of 8.6–17.3mg weekly
methylphen– idate	Daytrana	CII	10mg, 15mg, 20mg, 30mg	trans– dermal patches	—	• Apply patch to hip 2hrs before desired effect, remove 9hrs after application; may remove earlier if shorter duration of effect or late day side effect appears • May titrate dose at 1wk intervals
methylphen– idate HCl	—	CII	5mg	tabs	60mg/day in divided doses	• Give preferably 30−45min before meals
			10mg, 20mg	ext-rel tabs
			10mg, 20mg	scored tabs
			2.5mg, 5mg, 10mg	chew tabs	60mg/day in divided doses	• Give before breakfast and lunch
	Adhansia XR	CII	25mg 35mg, 45mg*, 55mg, 70mg, 85mg	ext-rel caps	Children: 85mg/day Adults: 100mg/day	• Give once daily in the AM • May titrate by 10–15mg at intervals of ≥5 days • May sprinkle contents on applesauce/yogurt and swallow immediately without chewing beads
	Aptensio XR	CII	10mg, 15mg, 20mg, 30mg, 40mg, 50mg, 60mg	ext-rel caps	≥6yrs: 60mg/day	• Give once daily in the AM • May titrate in increments of 10mg/day weekly • May sprinkle contents on applesauce and swallow without chewing beads
	Concerta	CII	18mg, 27mg, 36mg, 54mg	ext-rel tabs (with immediate-release outer coating)	6−12yrs: 54mg/day 13−17yrs: 72mg/day or 2mg/kg/day (whichever is less) ≥18yrs: 72mg/day	• Give once daily in the AM
	Jornay PM	CII	20mg, 40mg, 60mg, 80mg, 100mg	ext-rel caps	≥6yrs: 100mg/day	• Give once daily in the PM (between 6:30–9:30) • May titrate in 20mg increments weekly • May sprinkle contents on applesauce and swallow without chewing beads
	Metadate CD	CII	10mg, 20mg, 30mg, 40mg, 50mg, 60mg	ext-rel caps (containing immediate and ext‑rel beads)	≥6yrs: 60mg/day	• Give once daily in the AM before breakfast • May sprinkle contents on applesauce and swallow without chewing beads
	Methylin Oral Solution	CII	5mg/ 5mL, 10mg/ 5mL	oral soln	≥6yrs: 60mg/day in divided doses	• Give preferably 30−45min before meals
	Quillichew ER	CII	20mg, 30mg, 40mg	ext-rel chew tabs	≥6yrs: 60mg/day	• Give once daily in the AM • May titrate in increments of 10mg, 15mg, or 20mg
	Quillivant XR	CII	5mg/ mL	ext-rel oral susp	≥6yrs: 60mg/day	• Give once daily in the AM • Shake bottle vigorously for ≥10sec before use • May increase by 10–20mg weekly
	Ritalin	CII	5mg	tabs	≥6yrs: 60mg/day	• Give before breakfast and lunch
	Ritalin	CII	10mg, 20mg	scored tabs		• Give before breakfast and lunch
	Ritalin LA	CII	10mg, 20mg, 30mg, 40mg	ext-rel caps (half as immediate-release, half as e‑c delayed-release beads)	≥6yrs: 60mg/day	• Give once daily in the AM • May sprinkle contents on applesauce and swallow without chewing beads
mixed dextro– amphetamine/ amphetamine salts	—	CII	5mg, 7.5mg, 10mg, 12.5mg, 15mg, 20mg, 30mg	double-scored tabs	usually 40mg/day in 2−3 divided doses	• Give in AM and 4−6hrs apart
	Adderall XR	CII	5mg, 10mg, 15mg, 20mg, 25mg, 30mg	ext-rel caps	6–12yrs: 30mg/day	• Give once daily in the AM upon awakening • May sprinkle contents on applesauce and swallow without chewing beads
	Mydayis	CII	12.5mg, 25mg, 37.5mg, 50mg	ext-rel caps	13–17yrs: 25mg/day 18–55yrs: 50mg/day	• Give once daily in the AM • May increase by 12.5mg at weekly intervals • May sprinkle contents on applesauce and swallow without chewing beads
serdexmethyl– phenidate/ dexmethyl– phenidate	Azstarys	CII	26.1mg/ 5.2mg, 39.2mg/ 7.8mg, 52.3mg/ 10.4mg	caps	≥6yrs: 52.3mg/ 10.4mg daily	• Give once daily in the AM • May sprinkle contents into 50mL of water or over 2 tablespoons of applesauce and consume immediately
viloxazine	Qelbree	Rx	100mg, 150mg, 200mg	ext-rel caps	6–17yrs: 400mg/day	• Give once daily with or without food • May sprinkle contents on applesauce and swallow without chewing beads
NOTES
*Contains tartrazine Not an inclusive list of medications, official indications, or dosing information. Please see drug monograph at www.eMPR.com and/or contact company for full drug labeling. Use lowest effective dose. Avoid late evening doses. Re‑evaluate periodically; improvement may be sustained when the drug is either temporarily or permanently discontinued. If paradoxical aggravation of symptoms or other adverse effects occur, the dose should be reduced or discontinued. (Rev. 8/2021)

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Attention-Deficit/Hyperactivity Disorder General Psychiatry

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