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Bacterial infections
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Generic Name and Formulations:

Penicillin G benzathine, penicillin G procaine equal amounts; combined penicillin G dose 600,000Units/mL; susp for deep IM inj; contains parabens.


Pfizer Inc.

Select therapeutic use:

Indications for BICILLIN C-R:

Susceptible moderately severe infections including respiratory, skin and soft tissue, erysipelas, scarlet fever, otitis media.

Adults and Children:

C-R: Give by deep IM inj (buttock or, in young children, may give in anterolateral thigh). Group A strep: <30lbs: 600,000 units; 30–60lbs: 900,000–1.2 million units; >60lbs: 2.4 million units; all as single dose (may split injections) or may give one-half total dose on day 1 and one-half on day 3. Pneumococcal (except meningitis) children: 600,000 units; adults 1.2 million units; give every 2–3 days until afebrile for 48 hrs.


Avoid intraarterial, intravascular, and intraneural inj.


Not for IV use. Cephalosporin, imipenem, or other allergy: not recommended. Asthma. Monitor renal and hematopoietic function in prolonged use. Pregnancy (Cat.B). Nursing mothers.


Potentiated by probenecid. May cause false (+) glucose test with Clinitest.

See Also:

BICILLIN C-R 900/300

Pharmacological Class:

Penicillinase-sensitive penicillin.

Adverse Reactions:

Rash, drug fever, serum sickness, anaphylaxis, blood dyscrasias, neuropathy, nephropathy, inj site reactions.

How Supplied:

C–R Tubex 600,000 units/mL (1mL, 2mL)—10 (w. 1 inch or 1.25 inch needles); C–R disposable syringe 600,000 units/mL (4mL)—10 (w. 2 inch needles); C–R 900/300 Tubex 1.2 million units/syringe (2mL)—10 (w. 1 inch or 1.25 inch needles)