Traci Dantoni, Author at MPR - Page 3 of 7

Traci Dantoni

All articles by Traci Dantoni

Combination Morphine/Oxycodone Produces Less Oxygen Desaturation Than Morphine or Oxycodone Alone

In a study evaluating combination morphine/oxycodone, researchers found the drug to produce less oxygen desaturation in patients with acute postoperative pain than either single component alone when administered in equianalgesic doses. The results of the randomized, double-blind study were presented at the 2012 American Academy of Pain Medicine Annual Meeting.

Perioperative Infections: Less Frequent in Patients with Chronic Opioid Consumption?

Chronic opioid intake of ≥90 days may be associated with fewer perioperative infections; however, surgical technique and operating room environment — glucose, temperature, and hypoxia — “may play a larger role than opioid consumption in the occurrence of surgical site infection,” found a retrospective review of patients undergoing colectomy and lumbar spinal surgery presented during the 2012 American Academy of Pain Medicine Annual Meeting.

Lenalidomide + Azacitidine Well Tolerated, Highly Active in Patients with Higher-Risk Myelodysplastic Syndromes

A multicenter, Phase 2 continuation trial has shown that the positive overall response rate (ORR) seen in a Phase 1 trial evaluating lenalidomide + azacitidine combination therapy is substantiated, with good overall survival (OS), even among progressing patients, in a higher-risk myelodysplastic syndromes (MDS) population. The study was presented at the 53rd American Society of Hematology Annual Meeting and Exposition.