Traci Dantoni

Patients with fibromyalgia who have an inadequate response to duloxetine may gain additional benefit in global status and pain improvement when switched to milnacipran, according to research presented at the 2012 American Academy of Pain Medicine Annual Meeting.

Exclusive Video Interview: Dr. Gary Baker discusses the rates of abuse with tapentadol IR at the 2012 American Academy of Pain Medicine.

Patients who underwent multiple consecutive days of outpatient ketamine infusion for chronic neuropathic pain had minimal side effects and stable hemodynamics, a retrospective chart review presented during the 2012 American Academy of Pain Medicine Annual Meeting found.

In a study evaluating combination morphine/oxycodone, researchers found the drug to produce less oxygen desaturation in patients with acute postoperative pain than either single component alone when administered in equianalgesic doses. The results of the randomized, double-blind study were presented at the 2012 American Academy of Pain Medicine Annual Meeting.

Chronic opioid intake of ≥90 days may be associated with fewer perioperative infections; however, surgical technique and operating room environment — glucose, temperature, and hypoxia — “may play a larger role than opioid consumption in the occurrence of surgical site infection,” found a retrospective review of patients undergoing colectomy and lumbar spinal surgery presented during the 2012 American Academy of Pain Medicine Annual Meeting.

Capsaicin 8% patch is a novel therapy for the treatment of peripheral neuropathic pain. Researchers at the 2012 American Academy of Pain Medicine Annual Meeting reported on using mechanical pain sensitivity (MPS) to identify patients who are more likely to respond to capsaicin patch treatment in order to improve treatment targeting.

An analysis of the safety of duloxetine with concomitant nonsteroidal anti-inflammatory drug (NSAID) use found increased bleeding events in patients compared with nonusers of NSAIDs, investigators reported during the 2012 American Academy of Pain Medicine Annual Meeting.

In patients with postherpetic neuralgia (PHN), a once-daily formulation of gabapentin 1,800mg was found to be well tolerated and improved all dimensions of pain on the Neuropathic Pain Scale (NPS), according to results of a study presented at the 2012 American Academy of Pain Medicine Annual Meeting.

Diclofenac, a commonly prescribed nonsteroidal anti-inflammatory drug (NSAID), was shown to provide acute pain relief when administered as a nanoformulated, lower-dose formulation, according to results of a study presented at the 2012 American Academy of Pain Medicine Annual Meeting.

A multicenter, Phase 2 continuation trial has shown that the positive overall response rate (ORR) seen in a Phase 1 trial evaluating lenalidomide + azacitidine combination therapy is substantiated, with good overall survival (OS), even among progressing patients, in a higher-risk myelodysplastic syndromes (MDS) population. The study was presented at the 53rd American Society of Hematology Annual Meeting and Exposition.