MPR First Report

All articles by MPR First Report

Coping With Pain Related to Physical and Psychological Functioning

There is growing evidence that the way individuals cope with and appraise disease-related pain (e.g. arthritis pain and cancer) is not only related to their experience of pain but also to their physical and psychological functioning. Presenting at the American Pain Society 29th Annual Scientific Meeting, Francis J. Keefe, PhD, from Duke University Medical Center in Durham, N.C., reviewed the latest research in behavioral and psychosocial factors in pain and pain management.

Telcagepant Efficacy Unaffected by Prior Use of Opioids for Migraine

Does prior use of opioids for migraine headaches reduce responsiveness to subsequent acute migraine therapies, as limited evidence has suggested? Results of a post-hoc analysis of data from a randomized, double-blind, placebo-controlled trial suggest the answer is “no,” specifically regarding efficacy of telcagepant, a novel investigational oral calcitonin gene-related peptide receptor antagonist that has acute antimigraine efficacy comparable to oral triptans.
This was reported during the American Pain Society’s 29th Annual Scientific Meeting.