Lea Eslava-Kim, PharmD

Arimoclomol is a small molecule designed to amplify and sustain the cellular production of heat shock proteins, particularly HSP70, which targets protein misfolding and improves lysosomal function.

Nebulized ensifentrine, when added to tiotropium, produced clinically meaningful and significant improvements in lung function and quality of life in patients with COPD.

The FDA has approved Tivicay PD (dolutegravir; Viiv Healthcare) tablets for oral suspension, for the treatment of HIV-1 infection in treatment-naïve or -experienced but integrase inhibitor-naïve pediatric patients aged ≥4 weeks and weighing at least 3kg, in combination with other antiretroviral agents.

HIV-positive patients in the United States face significant challenges associated with poor adherence to antiretroviral therapy (ART) and HIV-1 drug resistance, according to a study published in AIDS and Behavior.

Antiretroviral drug dose adjustment based on age does not appear to be necessary in aging HIV patients, according to a pharmacokinetics study published in the British Journal of Clinical Pharmacology.

At Week 14, 22% of patients achieved resolution of neutrophilic inflammation, defined as NHI ≤1 or RHI ≤3 plus Geboes subgrades 2B.0/3.0. In the 13 patients who achieved clinical remission and 32 patients who achieved symptomatic remission, 77% and 44%, respectively

The following article is a part of conference coverage from the 2019 Advances in Inflammatory Bowel Diseases (AIBD) Meeting, being held in Orlando, Florida. The team at MPR will be reporting on the latest news and research conducted by leading experts gastroenterology. Check back for more from the 2019 AIBD Meeting. ORLANDO – Prescribing patterns…

The following article is a part of conference coverage from the 2019 Advances in Inflammatory Bowel Diseases (AIBD) Meeting, being held in Orlando, Florida. The team at MPR will be reporting on the latest news and research conducted by leading experts gastroenterology. Check back for more from the 2019 AIBD Meeting. ORLANDO – Treatment with…

Biosimilar BI 695501 demonstrated non-inferior efficacy and similar safety profile compared with the reference product adalimumab in patients with active Crohn disease.

GABA agonists for chronic pain, such as gabapentin and pregabalin, were not associated with higher prevalence of allergic rhinoconjunctivitis and asthma.