Jonathan Goodman, MPhil

Researchers sought to determine whether the COVID-19 mRNA vaccines were safe and effective in patients with transfusion-dependent beta-thalassemia.

Researchers sought to determine whether vaccination against COVID-19 would increase the risk of developing deep vein thrombosis.

Researchers sought to determine whether adding pevonedistat to azacitidine would improve outcomes for patients with higher-risk MDS, CMML, or AML.

Researchers sought to determine whether pegcetacoplan would be better than standard of care for treating patients with PNH.

Researchers sought to determine whether fitusiran prophylaxis would reduce the rate of bleeding events among patients with hemophilia A or B with inhibitors.

Researchers sought to determine whether lisocabtagene maraleucel would improve outcomes compared with standard of care in second-line therapy in patients with LBCL.

Predictors of worse progression-free survival included ISS stage II, ISS stage III, and adverse cytogenetics.

Researchers sought to determine whether zanubrutinib would improve survival in patients with treatment-naïve chronic lymphocytic leukemia/small lymphocytic lymphoma.

The association was observed with colon cancer but not rectal cancer.

Researchers sought to determine whether a combination therapy with bortezomib-augmented ASCT would have efficacy in patients with ultra high-risk multiple myeloma or plasma cell leukemia.