Acetaminophen 1,000mg does provide an incremental benefit vs. acetaminophen 650mg, reported Daniel Qi, from McNeil Consumer Healthcare, Fort Washington, PA, at the American Pain Society’s 31st Annual Scientific Meeting.
Naproxen significantly improved pain relief following arthroscopic surgery and reduced opioid utilization with no evidence of increased risk of adverse events, reported Evan Ekman, MD from Southern Orthopaedic Sports Medicine, Columbia, SC, at the American Pain Society’s 31st Annual Scientific Meeting.
Minimal systemic distribution of topical diclofenac sodium gel resulted in a lower incidence of major or moderate drug-drug interactions associated with oral diclofenac and reduced the risk of drug interaction-related adverse events. Study results were reported by Matthew Wieman, MD, from Endo Pharmaceuticals, John H. Peniston, DO, from Novartis Consumer Health, and colleagues at the American Pain Society’s 31st Annual Scientific Meeting.
Study investigators presented data from the UPLOAD (Understanding Pain & Limitations in OsteoArthritic Disease) study at the American Pain Society’s 31st Annual Scientific Meeting demonstrating that hydroxyvitamin D levels <25ng/mL were associated with an increase in osteoarthritis (OA) symptoms and a decreased threshold for pressure pain.
A randomized, placebo-controlled, double-blind study evaluating OROS hydromorphone ER for reducing moderate-to-severe osteoarthritis (OA) pain showed that though the treatment is effective in treating chronic OA, it failed to demonstrate sustained efficacy vs. placebo + rescue medication, “perhaps due to higher use of rescue medication in the latter group,” investigators concluded during a presentation at the American Pain Society’s 31st Annual Scientific Meeting.
Morning (vs. evening) dosing of extended-release (ER) hydromorphone appears to be associated with fewer respiratory events in patients with low-back pain and sleep-disordered breathing, according to a presentation at the 2012 American Academy of Pain Medicine Annual Meeting.
A single-tablet combination of ibuprofen 800mg and famotidine 26.6mg (HZT-501) administered three times daily was found to reduce nonsteroidal antiinflammatory drug (NSAID)-associated upper gastrointestinal (GI) ulcers in patients overall, as well as in each subset for those taking NSAIDs for osteoarthritis, rheumatoid arthritis, and chronic pain, a study presented during the 2012 American Academy of Pain Medicine Annual Meeting has found.
Daily use of long-acting opioids — vs. daily use of short-acting opioids — increases the risk of hypogonadism in men, one of the first studies to evaluate this association, presented during the 2012 American Academy of Pain Medicine Annual Meeting, has found.
Diclofenac sodium topical solution proved effective and well-tolerated in patients with heel pain, including plantar fasciitis, according to results of a study presented at the 2012 American Academy of Pain Medicine Annual Meeting.
Patients with chronic neuropathic pain can be safely and effectively converted and maintained on once-daily hydromorphone extended-release tablets (OROS hydromorphone ER), a study reported during the 2012 American Academy of Pain Medicine Annual Meeting.
