Cassandra Pardini, PharmD, Author at MPR

Cassandra Pardini, PharmD

All articles by Cassandra Pardini, PharmD

Diuretic Use Differences Examined in HFrEF Patients Treated With Sacubitril/Valsartan, Enalapril

For patients with heart failure with reduced ejection fraction (HFrEF), treatment with sacubitril/valsartan may aid in reducing the requirement for loop diuretics compared with enalapril, according to the results of a follow-up analysis of the Prospective comparison of ARNI with ACEI to Determine Impact on Global Mortality and morbidity in Heart Failure (PARADIGM-HF) trial.

Risk of Tendon Rupture With Fluoroquinolone Use Examined

According to a recently conducted review of cohort and nested case-control studies, the risk of both Achilles tendon and bicep tendon rupture is increased with administration of fluoroquinolones, however, the attributable risk is actually low. The review aimed to determine the relative, absolute, and attributable risk of tendon rupture associated with fluoroquinolone, as well as…