According to the results of a study reanalyzing data obtained from an FDA review, , ranolazine potentiates the effects associated with ACE inhibitors, as well as angiotensin receptor blockers.
Alirocumab, a proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibitor, was found to be both safe and effective in reducing low-density lipoprotein cholesterol (LDL-C) in patients with heterozygous familial hypercholesterolemia (HeFH) across different age groups, according to a post-hoc analysis.
For patients with heart failure with reduced ejection fraction (HFrEF), treatment with sacubitril/valsartan may aid in reducing the requirement for loop diuretics compared with enalapril, according to the results of a follow-up analysis of the Prospective comparison of ARNI with ACEI to Determine Impact on Global Mortality and morbidity in Heart Failure (PARADIGM-HF) trial.
Although the quality of evidence is low due to variable study designs, botulinum toxin may be beneficial in the treatment of chronic tension-type headaches for specific patients with clear treatment goals.
A recently published report describes the case of a 49-year-old female patient who experienced aplastic anemia secondary to long-term metronidazole use and highlights the importance of monitoring for metronidazole-induced hematologic dyscrasias.
Peppermint oil (PO) was found to be safe and effective in treating pain and global symptoms associated with irritable bowel syndrome (IBS) in adult patients, according to the results of a recently published systematic review and meta-analysis.
According to a recently conducted review of cohort and nested case-control studies, the risk of both Achilles tendon and bicep tendon rupture is increased with administration of fluoroquinolones, however, the attributable risk is actually low. The review aimed to determine the relative, absolute, and attributable risk of tendon rupture associated with fluoroquinolone, as well as…
Results of a recently published trial suggested pregabalin, a calcium channel alpha-2 delta ligand, may reduce gastrointestinal symptoms of irritable bowel syndrome.
A recently published report describes the case of a 16-year-old male patient who experienced a breakthrough seizure following ingestion of an energy drink and highlights the importance of recognizing drug-herb interactions and properly counseling patients on them.
A recently published study found that the majority of cardiac patients utilizing fish oil dietary supplements did so without the recommendation of a healthcare professional and without proper medical supervision.
