Asthma/COPD

Hailie Sensor Gets FDA Clearance for Additional Asthma Inhalers

By July 27, 2018

The Hailie sensor attaches to the asthma or chronic obstructive pulmonary disease (COPD) inhaler to monitor and help patient adherence.

Asthma Control and Atrial Fibrillation Risk: Is There a Link?

July 13, 2018

Dose-response association seen between levels of asthma control and risk of atrial fibrillation

Umeclidinium/Vilanterol Efficacy Assessed in Elderly COPD Patients

By July 06, 2018

Study authors performed a post hoc pooled analysis of data from 10 trials to assess the safety and efficacy of umeclidinium/vilanterol in elderly symptomatic patients with COPD.

Use of Palliative Care, Oxygen Therapy Increasing for COPD

July 03, 2018

Increase in use of formal palliative care services, long-term oxygen, but proportions still remain low

Patient Engagement in Asthma Treatment Plans May Improve Quality of Life

July 02, 2018

In older adults with asthma, decision making scores positively correlated with QoL scores

Combination of LABA + Inhaled Glucocorticoid Safe in Asthma

June 28, 2018

The researchers identified 3 asthma-related intubations (2 in the inhaled-glucocorticoid group, 1 in the combination therapy group) and 2 asthma-related deaths (both in the combination-therapy group) in 4 patients among the 36,010 patients in the intention-to-treat study.

Increased Risk of MI, Ischemic Stroke After COPD Exacerbation

June 19, 2018

Greater risks were seen following a severe exacerbation (incidence rate ratios, 2.58 and 1.97 for myocardial infarction and ischemic stroke, respectivley) than after a moderate exacerbation (incidence rate ratios, 1.58 and 1.45, respectively).

Respiratory Pathogens May Up Treatment Failure Risk in Asthma

June 07, 2018

There was a correlation for non-rhinovirus pathogens with increased absolute risk of treatment failure by 13.1%; specifically, by 8.8, 24.9, and 34.1% for respiratory syncytial virus, influenza, and parainfluenza, respectively.

Viruses not linked to asthma exacerbation severity

June 04, 2018

Identified viral pathogens were not associated with asthma exacerbation severity, but were linked to increased treatment failure. Evidence Rating Level: 2 (Good).

Two Novel Immune-Response Clusters Identified to RSV

May 18, 2018

"Distinct immune-response clusters during infant RSV infection and their association with risk of recurrent wheeze provide insights into the risk factors for and mechanisms of asthma development," the authors write.

Chemicals in Hair Products for Black Women Raise Concerns

May 18, 2018

Cyclosiloxanes, parabens, and the fragrance marker diethyl phthalate (DEP) were found at the highest levels, with DEP found most frequently.

Budesonide-Formoterol Used As Needed Beneficial in Mild Asthma

May 17, 2018

"These two trials show persuasively that treatment with budesonide-formoterol on an as-needed basis prevented the most serious outcomes of poorly controlled asthma," writes the author of an accompanying editorial.

Prescription Med Use in Children Down Overall From 1999 to 2014

May 16, 2018

Asthma medications, antibiotics, attention-deficit/hyperactivity disorder (ADHD) medications, topical agents, and antihistamines were the most commonly used medication classes in 2011 to 2014.

Asthma Mortality Inversely Tied to Deprivation in Young

May 15, 2018

The researchers observed a decrease in asthma mortality among more deprived groups at younger ages. Five- to 44-year-olds in the most deprived quintile had 19% lower mortality than those in the least deprived quintile (IRR, 0.81).

FDA Targets Clinics Offering Unapproved Stem Cell Therapies

May 11, 2018

The clinic claims its unapproved therapies can treat a number of serious diseases and conditions, including Parkinson's disease, amyotrophic lateral sclerosis (ALS), chronic obstructive pulmonary disease (COPD), heart disease, and pulmonary fibrosis.

Prevalence of Obese, Allergic Asthma Phenotypes Examined in US Children

By May 08, 2018

The study authors examined data obtained from the 2007-2008 National Survey of Children's Health (NSCH) to determine the prevalence, risk factors, as well as the severity of asthma phenotypes.

ICS Therapy May Not Be Enough for Asthma Patients With Elevated Eosinophils

By May 07, 2018

The study aimed to determine the association between ICS therapy adherence and the occurrence of asthma exacerbations in patients with high blood eosinophil levels.

Low Neighborhood Walkability Increases Risk of Asthma in Kids

May 07, 2018

There was an increased incidence of asthma among birth home neighborhoods with low walkability (hazard ratio, 1.11). Low walkability in a given year of a child's life was associated with greater odds of ongoing asthma in the same year (odds ratio, 1.12).

Most Concerning Med Issues Explored Among Youth With Asthma

By May 04, 2018

The study authors reported, "The most commonly reported problems by youth were: (a) hard to remember when to take the asthma medication (54%) and (b) hard to use asthma medication at school (34%)."

Feasibility of At-Home Use Injectable Tx for Severe Asthma Assessed

By May 03, 2018

Of the total 573 APFS dispensed, 1 malfunctioned and 1 was considered nonfunctional because it was not returned. The study authors also reported that patient-use error only led to 2 unsuccessful at-home administrations.

Disagreement Seen Over Barriers to Kids' Daily Use of Asthma Meds

April 25, 2018

"To tailor asthma management conversations, clinicians should understand family-specific barriers and child-caregiver disagreements," the authors write.

Trelegy Ellipta Gains Expanded COPD Indication, Loses Boxed Warning

By April 24, 2018

The drug consists of fluticasone furoate, an inhaled corticosteroid (ICS), umeclidinium, a long-acting muscarinic antagonist, and vilanterol, a long-acting beta2-adrenergic agonist (LABA), delivered via an Ellipta dry powder inhaler.

Psychosis Could Be a Potential Side Effect of Steroid Treatment in Kids

By April 12, 2018

Iatrogenic steroid-induced psychosis is a rare side effect of glucocorticoid therapy which is mostly seen in adults, although it has been reported in children and adolescents.

Considerable Differences in Burden of Disease at State Level

April 11, 2018

The highest and lowest life expectancies at birth were seen for Hawaii (81.3 years) and Mississippi (74.7 years) in 2016.

Tai Chi Helps Improve Respiratory Function in COPD

April 10, 2018

At the 12-week follow-up, the between-group difference for SGRQ favored the tai chi group (P<0.001). Similar results were seen for 6-minute walk distance, but there was no change in forced expiratory volume in one second.

Lonhala Magnair Now Available for Long-Term COPD Maintenance

By April 03, 2018

Lonhala Magnair is available as a 25mcg strength inhalation solution per 1mL vial.

Simple Lung Function Tests in Primary Care Help ID Early COPD

April 02, 2018

The researchers found that the most effective case-finding tools were the peak flow meter alone, the peak flow meter plus WheezoMeter, and microspirometry alone.

Two Inhalers Go Head-to-Head in COPD Exacerbation Study

By March 29, 2018

Study authors concluded, "Combining tiotropium and olodaterol did not reduce exacerbation rate as much as expected compared with tiotropium alone."

Smartinhaler Sensor for Symbicort Will Be Available Over-the-Counter

By March 27, 2018

The Smartinhaler sensor is a device installed onto a patient's inhaler to monitor and promote asthma and COPD medication adherence.

SCIT May Cut Long-Term Asthma Med Use in Pediatric Allergic Asthma

By March 26, 2018

Allergen avoidance, drug therapy, and allergen immunotherapy are all treatment options for allergic asthma.