Quintupling Glucocorticoid Dose: Is it Safe, Effective in Pediatric Asthma?

March 06, 2018

The researchers found that there was no significant difference between the groups in the rate of severe asthma exacerbations treated with systemic glucocorticoids but there was limited quadrupling dose of inhaled glucocorticoids may be beneficial for adolescents, adults with asthma

How Influential Is Family History in Childhood Asthma Development?

March 03, 2018

Children who had both parental and sibling asthma in their families had an increased risk for asthma.

Dupilumab Under FDA Review for Moderate-to-Severe Asthma

By March 02, 2018

Dupixent is a human monoclonal antibody specifically designed to inhibit signaling of interleukin-4 (IL-4) and interleukin-13 (IL-13), two important signaling proteins (cytokines) that contribute to Type 2 inflammation in moderate-to-severe asthma.

Impact of Asthma Medication on Fertility Examined in Women

February 27, 2018

No link to infertility for those with former asthma, or for those with asthma preventer medications

Combo LABA/LAMA Therapy Improves Cardiac Function in COPD

By February 23, 2018

Results demonstrated that after indacaterol-glycopyrronium treatment, left-ventricular end-diastolic volume increased from a mean 55.46mL/m2 (SD 15.89) at baseline to a least-squares (LS) mean of 61.76mL/m2 (95% CI 57.68-65.84).

Treatment Options for Patients With Severe Asthma

By February 16, 2018

Severe asthma is a challenging condition. Available therapeutic options for severe asthma include tiotropium, omalizumab, interleukin-5 targeted therapies, macrolide antibiotics, and bronchial thermoplasty.

Breath-Actuated Qvar RediHaler Available for Asthma Maintenance Treatment

By February 12, 2018

Qvar RediHaler (beclomethasone dipropionate HFA) Inhalation Aerosol is a breath-actuated inhaled prescription medicine used as a maintenance treatment for the prevention and control of asthma in people 4 years of age and older.

Asthma Guideline Adherence, Agreement Assessed Among PCPs, Specialists

By February 09, 2018

To examine real-world clinician adherence to these guidelines, as well as agreement and self-efficacy, researchers analyzed data from the 2012 National Asthma Survey of Physicians.

Does Long-Term ICS Use Increase Fracture Risk in COPD Patients?

By February 05, 2018

Long-term ICS exposure at high doses was associated with a modest but significant increase in the risk of hip or upper extremity fractures.

Telemedicine for Allergists Effective But May Need Ongoing Policy Guidelines

January 31, 2018

"The American College of Allergy, Asthma & Immunology will also need to monitor this rapidly changing landscape to ensure provision of high-quality care to the patient with allergic and immunologic disorders and consistency of practice in an era of futuristic technologies," the authors write.

New Starting Dose Approved for Daliresp to Treat Severe COPD

By January 29, 2018

The 250mcg dose approval was based on data from the Evaluation of Tolerability and Pharmacokinetics of Roflumilast, 250mcg and 500mcg, as add-on to Standard COPD Treatment to Treat Severe COPD (OPTIMIZE) study.

Asthma Treatment Aerospan Has Been Discontinued

By January 29, 2018

Both the 60- and 120-actuation sizes have been discontinued.

CDC: Certain Occupations Linked to Elevated Asthma Mortality

By January 19, 2018

The food, beverage and tobacco manufacturing industry (1.82) had the highest elevated asthma PMRs for men. Among women, the social assistance industry (1.35) and community social services occupations (1.46) had the highest elevated asthma PMRs.

Study Measures Economic Burden of Asthma in the U.S.

January 12, 2018

The per-person incremental medical cost of asthma differed from the population average for certain groups, including uninsured individuals ($2,145) and those living below the poverty line ($3,581).

Acid-Suppressive Drug Use During Pregnancy Linked to Asthma in Offspring

January 12, 2018

In pooled analysis, the researchers found that acid-suppressive drug use in pregnancy was associated with an increased risk of asthma in childhood.

School-based telemedicine enhances asthma management in children

January 10, 2018

A school-based telemedicine program with directly observed preventive therapy, when compared to enhanced usual care, led to more symptom-free days and fewer emergency department visits or hospitalizations.

New LABA, LAMA Use May Increase Cardiovascular Disease Risk in COPD

January 04, 2018

New use of long-acting 2-agonists, antimuscarinic antagonists tied to higher CVD risk in first 30 days

FDA: Boxed Warning About Asthma-Related Death Removed for LABA/ICS Combos

By December 21, 2017

The four trials also assessed efficacy of the ICS/LABA products.

Can Retraining How to Breath Improve Asthma Control?

December 14, 2017

Improvements in patients randomized to DVD and printed booklet intervention, face-to-face sessions.

Nucala Approved to Treat Rare Autoimmune Disease That Causes Vasculitis

By December 12, 2017

EGPA (formerly known as Churg-Strauss syndrome) is a condition characterized by asthma, high levels of eosinophils (a type of white blood cell that helps fight infection), and inflammation of small- to medium-sized blood vessels.

Sugar-Sweetened Drinks and Childhood Asthma Development: What's the Link?

December 11, 2017

The researchers found that comparing quartile 4 versus quartile 1, higher maternal pregnancy intake of sugar-sweetened beverages and total fructose correlated with increased odds of mid-childhood current asthma.

First Nebulized LAMA Approved for COPD

By December 06, 2017

Adults treated with Lonhala Magnair showed statistically significant and clinically important changes from baseline in trough forced expiratory volume in 1 second (FEV1) at Week 12 vs placebo.

Fasenra Approved for Severe Eosinophilic Asthma

By November 15, 2017

Fasenra is indicated for the add-on maintenance treatment of patients with severe asthma aged 12 years and older, and with an eosinophilic phenotype.

NDA Submitted for Revefenacin for the Treatment of COPD

By November 14, 2017

In the Phase 3 trials revefenacine demonstrated statistically significant and clinically meaningful improvements compared to placebo in trough forced expiratory volume in 1 second (FEV1).

Does Inhaled Corticosteroid Use Up the Risk of Fracture in Children?

November 14, 2017

Inhaled corticosteroids are not associated with increased odds of fracture in the pediatric asthma population

Dupilumab Beneficial for Patients with Severe Steroid-Dependent Asthma

By October 31, 2017

Consistent reductions in asthma attacks and improvements in lung function across a broad population of uncontrolled asthma patients.

Bedside to 'Webside' Manner: Leveraging Telemedicine in Health Care Delivery

October 30, 2017

The same standards of care, professionalism, and ethics should be in place for live interactive video visits with patients as for in-person consultations, said the panelists.

COPD Exacerbation Risk Reduced With LAMA Plus LABA

October 04, 2017

Also might result in greater improvement in FEV1 than LABA plus corticosteroids

Pneumococcal Vaccine Rates Assessed by Work-Related Asthma Status

September 28, 2017

The researchers found that 42% of the estimated 12 million ever-employed adults with current asthma had received a pneumococcal vaccine. The likelihood of receiving a pneumococcal vaccine was increased for adults with work-related asthma versus those with non-work-related asthma.

Asthma Drug Linked to Neuropsychiatric Adverse Events

By September 21, 2017

Results found that overall depression was the most commonly reported adverse event in the VigiBase group while headaches were the most frequent adverse event reported for the Dutch database.