Allergic Disorders

Alternative Grass Peptide Tx Shows Promise in Reducing Allergy Symptoms

March 16, 2018

Compared to the placebo group, the LPP group had reduced reactivity to a conjunctival provocation test (P<0.001) and, during the pollen season, a lower rhinoconjunctivitis quality of life global score (P=0.005).

Symjepi vs EpiPen: Incorrect Usage Rates Among Untrained Teens

By March 08, 2018

The study enrolled 34 adolescents aged 12 to 17 years old who had no familiarity with an epinephrine device (naive) and did not receive training during the study.

Peanut Allergy Oral Immunotherapy Effective in Phase 3 Study

By February 21, 2018

With regard to adverse events, 12.4% of AR101-treated patients discontinued treatment due to treatment-related side effects; these included gastrointestinal adverse events (6.7%) and systemic allergic hypersensitivity reactions (2.7%).

Survey: Most At-Risk Patients Don't Carry Two Epinephrine Auto-Injectors

By February 08, 2018

Most respondents did not carry 2 EAIs in order to keep 1 EAI in another location.

Varubi Labeling Updated to Warn of Serious Hypersensitivity Reactions

By January 16, 2018

Anaphylaxis, anaphylactic shock and other serious hypersensitivity reactions have been reported.

Odactra Available for House Dust Mite-Induced Allergic Rhinitis

By January 10, 2018

Odactra is an allergen extract indicated as immunotherapy for house dust mite (HDM)-induced allergic rhinitis.

New Flu Vaccine Guidelines Issued for Patients With Egg Allergy

By December 19, 2017

The updated parameter stresses that no special precautions are needed or recommended for those with egg allergy.

Allergen Concentrations Higher in Day-Care Centers Than Homes

December 14, 2017

The vast majority of DCC samples were positive for allergens, including domestic mite allergens (96%), dog allergens (95%), cat allergens (90%), and mouse allergens (83%).

Omalizumab May Benefit Patients With Allergies to Multiple Foods

December 12, 2017

Findings in multifood allergic pediatric patients

Auvi-Q 0.1mg Auto-Injector Approved for Infants, Small Children

By November 20, 2017

Auvi-Q 0.1mg is the first epinephrine auto-injector specifically designed for the treatment of life-threatening allergic reactions, including anaphylaxis, in infants and small children weighing 16.5 to 33 pounds.

Epicutaneous Immunotherapy for Peanut Allergy Investigated

November 15, 2017

250-g patch produces significant treatment response compared with placebo after 12 months

FlutiCare Nasal Spray Now Available OTC to Relieve Allergy Symptoms

By November 14, 2017

FlutiCare will be available OTC with the same prescription strength and same delivery method as Flonase and ClariSpray.

Seasonal Allergic Rhinitis Treatment Guidelines Updated

By November 07, 2017

The guidelines focus on three key clinical statements.

HydraSense Nasal Care Line Available for Infants and Children

By November 01, 2017

hydraSense hydrates and soothes dry and uncomfortable nasal passages.

Fish Consumption May Trigger Food Protein-Induced Enterocolitis

October 31, 2017

The number of reactions before diagnosis was four on average. The main symptoms at the debut were vomiting and vomiting with diarrhea (97.5 and 30%, respectively), which occurred in a mean time of 126.3 minutes after ingestion of the culprit fish.

Bedside to 'Webside' Manner: Leveraging Telemedicine in Health Care Delivery

October 30, 2017

The same standards of care, professionalism, and ethics should be in place for live interactive video visits with patients as for in-person consultations, said the panelists.

Are Pediatricians Addressing the Topic of Early Peanut Introduction With Parents?

By October 27, 2017

Of those who completed the survey, 38% scored a 1 or lower on whether they complied with guidelines.

Co-Occurrence of Autoimmunities for Diabetes, Celiac Disease Examined

October 11, 2017

The researchers found that IAs alone, tTGAs alone, and both appeared in 367, 808, and 90 children, respectively, with co-occurrence significantly exceeding the expected rate.

Early-Life Antibiotic Use and Celiac Disease: Is There an Association?

October 10, 2017

The researchers found that exposure to and frequency of use of any antibiotic assessed in the study in early life or before seroconversion was not associated with the risk of developing islet or celiac disease autoimmunity.

Asthma Drug Linked to Neuropsychiatric Adverse Events

By September 21, 2017

Results found that overall depression was the most commonly reported adverse event in the VigiBase group while headaches were the most frequent adverse event reported for the Dutch database.

Xolair Re-Treatment Still Effective in Chronic Spontaneous Urticaria

By September 19, 2017

Among the re-treated patients, almost 90% achieved symptom control (UAS7 ≤6) within 3 months. During both dosing periods, Xolair 150mg and 300mg were well-tolerated

AAP: School Workers Should Be Trained in Epinephrine Admin

September 19, 2017

Fifteen percent of participants reported that at least 1 dose of epinephrine was administered in their school by anyone, themselves included, in 2015 to 2016, compared with 24% in 2014 to 2015.

Possible Diagnostic, Therapeutic Target ID'd for Child Milk Allergies

September 13, 2017

The researchers found that among the micro RNAs (miRNAs) differently expressed, 2 were up-regulated and 14 were down-regulated in children with active CMA versus healthy controls.

Researchers Develop Portable Food Allergen-Detection System

By September 07, 2017

Most products were accurate to their stated label, however most products did contain at least 1 unspecified antigen, for instance, "brand of nut-free cookies contained gluten, whereas a gluten-free brand contained a peanut allergen," the authors write.

Penicillin Safety in Those with Allergy History But Negative Skin Test

By August 24, 2017

The authors reported that zero patients developed an immediate hypersensitivity reaction during these courses of administration.

Peanut Allergy Tx Efficacy Examined in 4-Year Follow-Up Study

By August 17, 2017

Results found that 4 children initially treated with PPOIT and 6 treated with placebo had allergic reactions to peanut intake, none experience prophylaxis.

Celiac Disease Linked to Increased Risk of Pneumococcal Infection

By August 15, 2017

After adjusting for socioeconomic index, diabetes, level of education, sex and age, an increased risk of pneumococcal infection among celiac disease patients was noted.

FDA: Severe Hypersensitivity, Death Following Curcumin Injection

By August 04, 2017

In March and May 2017, two patients given intravenous (IV) infusions of curcumin emulsion compounded with polyethylene glycol (PEG) 40 castor oil reported having immediate hypersensitivity reactions.

House Dust Mites May Induce lgE Sensitization to Antigens for Some

July 28, 2017

Researchers used IgE immunoblotting to analyze plasma samples from 179 atopic dermatitis patients for IgE-reactivity to a panel of micro-arrayed house dust mites allergen molecules.

Epinephrine Auto-Injector for Infants, Small Children Gets Priority Review

By July 27, 2017

The company has indicated that if the new auto-injector is approved they expect it to be available for patients in the first half of 2018.