Researchers examined seizure outcome at 6 months following slow initiation of KD in 40 children. The diet was initiated at a very low ratio (0.6 to 1:1) and was increased gradually depending on the tolerability and desired seizure control.
Researchers assessed the relationship between maternal antibiotic use and neonatal seizures in infants (>32 weeks gestation).
When compared to lamotrigine, levetiracetam was found to increase seizure-freedom, however, it was also associated with an increased risk of side effects.
Odds of achieving a clinically meaningful (≥50%) or substantial (≥75%) reduction in convulsive seizure frequency were 29 and 50 times higher, respectively, among patients treated with ZX008 than in patients treated with placebo.
For all POS and for most POS subtypes, pregabalin resulted in a numerically greater percentage of subjects who exhibited categorical decreases in seizure frequency vs placebo.
Trends of suicide related behavior were compared before and after initiation of AED therapy among AED users with and without epilepsy to individuals without AED use.
At baseline, the patients included in the study were an average (SD) age of 12.4 (9.0) years old with an average (SD) 86.6 (161.5) drop seizures/week.
Researchers compared outcomes between patients treated with continuous infusion or repeated doses of nonbenzodiazepine anti-seizure medication.
Cannabidiol in oral solution was evaluated for safety, drop-seizure frequency, total-seizure frequency, and S/GIC change in patients with Lennox-Gastaut Syndrome.
Treatment with positive airway pressure may help retain or improve seizure control in patients with epilepsy and obstructive sleep apnea.
Results found that infants with an unknown epilepsy etiology, a normal MRI, an EEG displaying hypsarrhythmia, or those already receiving an AED were more likely to be administered ACTH.
The study had a 70.0% responder rate and there was a 30.9% seizure freedom rate after 12 months of ESL treatment for patients transitioning from carbamazepine due to lack of efficacy.
Approximately one-third of pediatric patients with refractory convulsive status epilepticus develop neurologic deficits.
The Tablet's display includes more customizable info on electrocorticographic trends and there are now less steps needed to adjust settings.