Addiction/dependence

FDA to Review Long-Acting Treatment for Opioid Use Disorder

By July 16, 2018

Pending approval, CAM2038 may be the first long-acting treatment for OUD in both weekly and monthly formulations.

Misleading Popular Videos Impact Attitudes About Tobacco

July 11, 2018

"In the context of our findings, young adults should be trained in identifying and resisting contents that appear on social media, but share many of the characteristics of peer pressure to use unhealthy products," the authors write.

High Rates of <i>Salmonella</i> Contamination ID'd in Kratom

July 10, 2018

Of 81 samples of kratom collected for testing, 42 (52%) were contaminated with Salmonella, indicating that a high proportion of kratom being shipped into the United States may be contaminated.

Case Report Details Use of Buprenorphine for Treatment of Kratom Dependence

By July 06, 2018

In their article, the authors report on two patients who used kratom to self-treat their chronic pain after they could no longer receive opioid analgesics from healthcare providers.

Cannabis Use Prevalence Up Across Adult Age Groups

June 26, 2018

No significant differences in increases were seen across adult ages 18 to 64 years; the increases ranged between 1 and 2 percentage points.

Insurance Company Sets Goal for Reducing Opioid Overdoses by 25%

By June 22, 2018

Through their predictive analytics, Cigna can identify customers most likely to suffer from an overdose and can prompt interventions.

Drug treatment associated with a significant reduction in death risk following opioid overdose

June 22, 2018

Buprenorphine and methadone maintenance treatment (MMT) was associated with reduced death in opioid users.

NIH Initiative Aims to Address Opioid Misuse Over Long Term

June 21, 2018

Pain management could be enhanced by research to develop a better understanding of chronic pain and development of new non-addictive pain treatments. To speed movement of non-addictive treatments through the clinical pipeline, a public-private HEAL partnership is planned.

Cannabis Use Linked to Psychosis Symptoms in Adolescents

June 19, 2018

These correlations were similar in size to the autoregressive link between PS from ages 15 to 16. There was a statistically significant association for PS at age 15 years with cannabis use at age 16 years.

CDC: Many High School Students Engage in Health-Risk Behaviors

June 19, 2018

Many high school students were engaged in behaviors associated with chronic disease; 8.8% had smoked cigarettes and 13.2% had used an electronic vapor product on at least 1 day during the past 30 days.

First Generic Versions of Suboxone Get FDA Approval for Opioid Dependence

By June 15, 2018

The treatment combines buprenorphine, a partial-opioid agonist, with naloxone, an opioid antagonist.

Wearable Device Cleared for Use During Opioid Detoxification

By June 12, 2018

Electrical pulses are sent through small needles that are inserted in the ear to combat the early stages of detoxification, leading to stabilization.

Synthetic Cannabis May Increase Ischemic Cardiomyopathy Risk

June 08, 2018

Ischemic cardiomyopathy described in young male, which was attributed to synthetic cannabinoid use

AAFP Joins Call on FDA to Reduce Nicotine Content in Cigarettes

June 07, 2018

The FDA suggests that 5 million adult smokers could quit within 1 year of implementation; furthermore, 33 million people could avoid becoming regular smokers by the end of the century.

USPSTF Advises PCPs to Screen Adults for Unhealthy Alcohol Use

June 06, 2018

"The Task Force once again found that screening adults and providing brief counseling in primary care settings can help detect and reduce unhealthy alcohol use," Task Force member Carol Mangione, MD, said in a statement.

Tighter Alcohol Policies Cut Alcohol-Related Crash Deaths

May 30, 2018

For each 10-percentage point increase in the Alcohol Policy Scale score (more restrictive state policies) there was a reduced individual-level odds of alcohol involvement in a crash fatality (adjusted odds ratio, 0.90).

Long-acting buprenorphine depots may be efficacious for opioid use disorder

May 22, 2018

In this double-blind randomized controlled trial, weekly or monthly buprenorphine depot injections were non-inferior to daily sublingual buprenorphine/naloxone in maintaining no evidence of illicit opioid use at 24 weeks in outpatients with opioid use disorder (OUD).

Patterns of Potential Misuse Help Assess Risk of Opioid Overdose

May 22, 2018

There was a positive correlation for subsequent opioid overdose with successively greater numbers of prescribers or pharmacies or higher opioid quantities during the index period.

First Non-Opioid Drug Approved for Managing Opioid Withdrawal Symptoms

By May 17, 2018

Lucemyra, a selective alpha 2-adrenergic receptor agonist, works by reducing the release of norepinephrine and decreasing sympathetic tone.

Reported Cannabis Use Up in Parents With Children in Home

May 14, 2018

Data were obtained from the National Survey on Drug Use and Health from 2002 to 2015. The researchers did not have information on the method of cannabis use (ie, smoking versus edible forms).

Novel Thirdhand Smoke Exposure Route Identified

May 11, 2018

The chemical residue from cigarette smoke that attaches to anything and anyone in the vicinity of a smoke cloud, can still make its way into the air of buildings that currently have a non-smoking designation.

Walmart Plans on Restricting Supply on Acute Opioid Prescription Fills

By May 08, 2018

For states that currently limit new acute opioid prescription fills to <7 days, Walmart and Sam's Club pharmacies will follow that state law.

Child Secondhand Pot &#43; Tobacco Exposure Ups Risk for ER Visits

May 07, 2018

The rate of emergency department visitation was similar for all groups, except the marijuana plus tobacco group, which had a significantly higher rate of emergency department visits compared with controls.

Synthetic Opioid Involvement in Opioid-Related Deaths Up

May 02, 2018

From 2010 to 2016, synthetic opioid involvement up from 14.3 to 45.9 percent of opioid-related deaths

Knowledge Not Tied to Addictive Tanning Behavior in Millennials

April 27, 2018

Furthermore, motivation for perceived appearance enhancement was a significant predictor of addictive tanning behavior. The correlation between narcissism and additive tanning was mediated by appearance motivation.

Substance Use Disorders Linked to Conversion to Schizophrenia

April 26, 2018

This prospective cohort study included a population-based sample of 2,539 individuals born in Denmark with an incident diagnosis of schizotypal disorder and without a previous diagnosis of schizophrenia.

Pros and Cons for E-Cigarettes As Aid to Smoking Cessation

April 26, 2018

The authors note that e-cigarettes seem to double the likelihood of achieving abstinence and are as effective as nicotine replacement therapy for supporting cessation.

Alcohol Intake May Influence Oral Microbiome Composition

April 24, 2018

Subjects with higher alcohol consumption had certain genera that were enriched, including Actinomyces, Leptotrichia, Cardiobacterium, and Neisseria; some of these genera contain oral pathogens, and Neisseria can synthesize alcetaldehyde from ethanol.

Pediatric Exposures to Liquid Nicotine Down From 2015 to 2016

April 23, 2018

Comparing the 9 months before with the nine months after the federal child-resistant packaging law went into effect, there was a significant decrease in the mean number of exposures among states without a preexisting law requiring child-resistant packaging, averaging 4.4 fewer exposures per state after law implementation.

Questions Surround Concept of Internet Gaming Disorder

April 23, 2018

Definitions are heterogeneous; the proposed definition in the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition, provides a good starting point for diagnosing IGD, although there are some disadvantages.