Increased Risk of Depression, Suicide in Atopic Dermatitis

Higher depression scales, antidepressant use, and suicidality significantly associated with atopic dermatitis.
Higher depression scales, antidepressant use, and suicidality significantly associated with atopic dermatitis.

This article is part of MPR's coverage of the ACAAI 2018 meeting, taking place in Seattle, Washington. Our staff will report on medical research related to allergy, asthma, and more conducted by experts in the field. Check back regularly for more news from ACCAI 2018.


SEATTLE — Patients with atopic dermatitis have an increased risk for depression and suicidality, according to an abstract presented at the American College of Allergy, Asthma, and Immunology Scientific Meeting, held November 15-19, 2018, in Seattle.

Researchers of this systematic review searched for all observational studies in applicable databases related to depression rates in patients with atopic dermatitis. Data were abstracted and pooled using random effects weighting, and publication bias was not observed.

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A total of 36 studies were included in the meta-analysis. The prevalence of depression in patients with atopic dermatitis was 20.1% and 14.8% in patients without atopic dermatitis. Higher depression scales, parental depression, antidepressant use, and suicidality were all significantly associated with atopic dermatitis.

The researchers concluded that there is a “complex relationship between [atopic dermatitis] and depression,” and patients with atopic dermatitis have an increased chance of developing depression and suicidality.

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Reference

Patel K, Immaneni S, Singam V, Rastogi S, Silverberg J. A systematic review and meta-analysis of depression and suicide in atopic dermatitis. Presented at: the Annual Scientific Meeting of the American College of Allergy, Asthma, and Immunology; November 15-19, 2018; Seattle, WA. Abstract A500.