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Switching to Long-Acting Injectable Effective in Schizophrenia Patients Previously on Oral Therapy

A study published in Psychopharmacology concludes that stable, non-acute but symptomatic patients taking oral antipsychotic monotherapy may experience clinically meaningful improvement in symptoms, functioning, and treatment satisfaction after direct switch to paliperidone palmitate once-monthly injection.  A team of researchers conducted a post-hoc analysis of a prospective, interventional, single-arm, international, multicenter, open-label, 6-month study to investigate the safety, tolerability, and…
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Managing Antipsychotic-Induced Somnolence: A Review

Antipsychotic-induced somnolence should be managed with sleep hygiene education, selecting an antipsychotic with a lower risk of somnolence, and initiating at a lower dose with a slower titration based on psychiatric diagnoses, a review published in CNS Drugs stated.